# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4321988 | B | Binding affinity to human recombinant Nav1.4 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
2. | ALA4321989 | B | Binding affinity to human recombinant Nav1.5 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
3. | ALA4322009 | A | Unbound fraction in mouse plasma | Mus musculus | 5 | ALA4321785 | cell-free format | Scientific Literature | |
4. | ALA4322010 | A | Ratio of unbound plasma concentration in mouse model of inherited erythromelalgia to Kd for binding affinity to recombinant human Nav1.7 by radioligand binding assay | 2 | ALA4321785 | assay format | Scientific Literature | ||
5. | ALA4322011 | A | Ratio of unbound plasma concentration in mouse model of formalin-induced pain to Kd for binding affinity to mouse Nav1.7 by radioligand binding assay | Mus musculus | 2 | ALA4321785 | assay format | Scientific Literature | |
6. | ALA4322012 | A | Ratio of unbound plasma concentration in mouse model of CFA-induced cold allodynia to Kd for binding affinity to mouse Nav1.7 by radioligand binding assay | Mus musculus | 2 | ALA4321785 | assay format | Scientific Literature | |
7. | ALA4322013 | A | Ratio of unbound plasma concentration in mouse model of SNI-induced pain to Kd for binding affinity to mouse Nav1.7 by radioligand binding assay | Mus musculus | 1 | ALA4321785 | assay format | Scientific Literature | |
8. | ALA4322014 | A | Ratio of unbound plasma concentration in mouse model of STZ-induced pain measured on day 1 to Kd for binding affinity to mouse Nav1.7 by radioligand binding assay | Mus musculus | 1 | ALA4321785 | assay format | Scientific Literature | |
9. | ALA4322019 | B | Binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
10. | ALA4322020 | B | Binding affinity to mouse Nav1.7 by radioligand binding assay | Mus musculus | 2 | ALA4321785 | single protein format | Scientific Literature | |
11. | ALA4322021 | B | Binding affinity to human recombinant Nav1.1 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
12. | ALA4322022 | B | Binding affinity to human recombinant Nav1.2 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
13. | ALA4322023 | B | Binding affinity to human recombinant Nav1.3 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
14. | ALA4322024 | B | Binding affinity to human recombinant Nav1.6 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | single protein format | Scientific Literature | |
15. | ALA4322025 | B | Binding affinity to mouse Nav1.8 TTX-resistant current by radioligand binding assay | Mus musculus | 2 | ALA4321785 | single protein format | Scientific Literature | |
16. | ALA4322026 | B | Selectivity ratio of Kd for binding affinity to human recombinant Nav1.1 by radioligand binding assay to Kd for binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | assay format | Scientific Literature | |
17. | ALA4322027 | B | Selectivity ratio of Kd for binding affinity to human recombinant Nav1.2 by radioligand binding assay to Kd for binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | assay format | Scientific Literature | |
18. | ALA4322028 | B | Selectivity ratio of Kd for binding affinity to human recombinant Nav1.3 by radioligand binding assay to Kd for binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | assay format | Scientific Literature | |
19. | ALA4322029 | B | Selectivity ratio of Kd for binding affinity to human recombinant Nav1.4 by radioligand binding assay to Kd for binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | assay format | Scientific Literature | |
20. | ALA4322030 | B | Selectivity ratio of Kd for binding affinity to human recombinant Nav1.5 by radioligand binding assay to Kd for binding affinity to human recombinant Nav1.7 by radioligand binding assay | Homo sapiens | 2 | ALA4321785 | assay format | Scientific Literature |