| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4354314 | B | Displacement of [125I]-alpha-bungarotoxin from alpha7 nAChR in Wistar rat brain membrane incubated for 3 hrs by gamma counting analysis | Rattus norvegicus | 47 | cell membrane format | Scientific Literature | ||
| 2. | ALA4354321 | B | Agonist activity at alpha7 nAChR in human SH-SY5Y cells assessed as increase in intracellular calcium release at 50 nM preincubated for 1 min with alpha7 nAchR PAM PNU120596 prior to compound addition by Fluo-3 AM staining-based fluorescence spectral scanning multimode reader analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4354322 | B | Agonist activity at alpha7 nAChR in human SH-SY5Y cells assessed as release of intracellular calcium at 50 nM preincubated for 20 mins with alpha7 nAChR antagonist alpha-bungarotoxin and for 1 min with alpha7 nAChR PAM PNU120596 prior to compound addition by Fluo-3 AM staining-based fluorescence spectral scanning multimode reader analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4354325 | B | Displacement of [3H]cytisine from human recombinant alpha4beta2 nAChR incubated for 120 mins by radiometric scintillation analysis | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
| 5. | ALA4354326 | B | Displacement of [3H]BRL 43694 from human 5HT3R by radioligand displacement assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA4354347 | A | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 50 nM to 5 uM incubated for 48 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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