# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4383162 | B | Binding affinity to Pseudomonas aeruginosa PAO1 NB52019 LpxC after 60 to 420 secs by SPR method | Pseudomonas aeruginosa PAO1 | 16 | ALA4382199 | single protein format | Scientific Literature | |
2. | ALA4383163 | F | Antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 after 20 hrs by CLSI protocol-based microdilution assay | Pseudomonas aeruginosa | 16 | ALA4382199 | organism-based format | Scientific Literature | |
3. | ALA4383164 | F | Antimicrobial activity against Escherichia coli ATCC 25922 after 20 hrs by CLSI protocol-based microdilution assay | Escherichia coli | 16 | ALA4382199 | organism-based format | Scientific Literature | |
4. | ALA4383165 | F | Antimicrobial activity against Klebsiella pneumoniae ATCC 43816 after 20 hrs by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 18 | ALA4382199 | organism-based format | Scientific Literature | |
5. | ALA4383166 | P | Lipophilicity, log D of the compound at pH 7.4 | 15 | ALA4382199 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4383182 | B | Inhibition of LpxC in Klebsiella pneumoniae ATCC 43816 assessed as antibacterial activity after 20 hrs in presence of rifampicin by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 6 | ALA4382199 | assay format | Scientific Literature | |
7. | ALA4383183 | B | Inhibition of LpxC in Klebsiella pneumoniae ATCC 43816 assessed as antibacterial activity after 20 hrs in presence of vancomycin by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 6 | ALA4382199 | assay format | Scientific Literature | |
8. | ALA4383184 | B | Inhibition of LpxC in Klebsiella pneumoniae ATCC 43816 assessed as potentiation factor by measuring ratio of MIC of compound alone to MIC of compound in presence of rifampicin after 20 hrs by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 6 | ALA4382199 | assay format | Scientific Literature | |
9. | ALA4383185 | B | Inhibition of LpxC in Klebsiella pneumoniae ATCC 43816 assessed as potentiation factor by measuring ratio of MIC of compound alone to MIC of compound in presence of vancomycin after 20 hrs by CLSI protocol-based microdilution assay | Klebsiella pneumoniae | 6 | ALA4382199 | assay format | Scientific Literature |