# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4409077 | B | Inhibition of FAAH in mouse brain membranes using [14C]-AEA as substrate incubated for 15 mins by scintillation counting method | Mus musculus | 11 | ALA4406846 | cell membrane format | Scientific Literature | |
2. | ALA4409078 | B | Inhibition of FAAH in mouse brain membranes assessed as inhibitory constant using [14C]-AEA as substrate incubated for 15 mins by scintillation counting method | Mus musculus | 10 | ALA4406846 | cell membrane format | Scientific Literature | |
3. | ALA4409079 | B | Displacement of [3H]-spiperone from human D2 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation counting method | Homo sapiens | 11 | ALA4406846 | cell-based format | Scientific Literature | |
4. | ALA4409080 | B | Displacement of [3H]-spiperone from human D3 receptor expressed in CHO cells co-expressing Galpha16 incubated for 120 mins by liquid scintillation counting method | Homo sapiens | 11 | ALA4406846 | cell-based format | Scientific Literature | |
5. | ALA4409081 | B | Inhibition of human ERG expressed in HEK293 cells incubated for 72 hrs by patch clamp assay | Homo sapiens | 11 | ALA4406846 | cell-based format | Scientific Literature | |
6. | ALA4409082 | B | Displacement of [3H]CP55, 940 from mouse brain membrane CB1 receptor | Mus musculus | 2 | ALA4406846 | assay format | Scientific Literature | |
7. | ALA4409083 | B | Displacement of [3H]CP55, 940 from mouse brain membrane CB2 receptor | Mus musculus | 2 | ALA4406846 | assay format | Scientific Literature | |
8. | ALA4409084 | B | Inhibition of MAGL in mouse brain assessed as release of [3H]glycerol using [3H]-2-OG as substrate incubated for 30 mins by scintillation counting method | Mus musculus | 2 | ALA4406846 | tissue-based format | Scientific Literature | |
9. | ALA4409085 | P | Solubility of compound in DMSO at pH 3 incubated for 12 hrs by HPLC/UV/DAD analysis | 2 | ALA4406846 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4409086 | P | Solubility of compound in DMSO at pH 7.4 incubated for 12 hrs by HPLC/UV/DAD analysis | 2 | ALA4406846 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4409087 | P | Chemical stability of compound in DMSO assessed as remaining compound at pH 3 incubated for 24 hrs by HPLC/UV/DAD analysis | 2 | ALA4406846 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4409088 | A | Cytotoxicity against mouse NIH/3T3 cells assessed as cell viability incubated for 24 hrs by neutral red uptake based assay | Mus musculus | 3 | ALA4406846 | cell-based format | Scientific Literature | |
13. | ALA4409089 | A | Cytotoxicity against human U373MG cells assessed as cell viability incubated for 24 hrs by neutral red uptake based assay | Homo sapiens | 2 | ALA4406846 | cell-based format | Scientific Literature | |
14. | ALA4409094 | A | Metabolic stability in rat liver microsomes assessed as apparent decay constant at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Rattus norvegicus | 2 | ALA4406846 | microsome format | Scientific Literature | |
15. | ALA4409095 | A | Metabolic stability in rat liver microsomes assessed as intrinsic clearance at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Rattus norvegicus | 2 | ALA4406846 | microsome format | Scientific Literature | |
16. | ALA4409096 | A | Metabolic stability in rat liver microsomes assessed as half life at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Rattus norvegicus | 2 | ALA4406846 | microsome format | Scientific Literature | |
17. | ALA4409097 | A | Metabolic stability in human liver microsomes assessed as apparent decay constant at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Homo sapiens | 2 | ALA4406846 | microsome format | Scientific Literature | |
18. | ALA4409098 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Homo sapiens | 2 | ALA4406846 | microsome format | Scientific Literature | |
19. | ALA4409099 | A | Metabolic stability in human liver microsomes assessed as half life at 5 uM incubated for 60 mins by UV-Vis spectrophotometry | Homo sapiens | 2 | ALA4406846 | microsome format | Scientific Literature | |
20. | ALA4409100 | A | Cytotoxicity against human IMR32 cells at 0.1 to 50 uM incubated for 24 hrs by LDH release assay | Homo sapiens | 2 | ALA4406846 | cell-based format | Scientific Literature |