| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395242 | B | Inhibition of STAT3 in human MDA-MB-231 cells assessed as decrease in STAT3-DNA binding at 1 to 4 uM incubated for 24 hrs by electrophoretic mobility shift assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 2. | ALA4395243 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 1 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 95.1%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 3. | ALA4395244 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 3.2%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 4. | ALA4395245 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 17 | ALA4393689 | cell-based format | Scientific Literature | |
| 5. | ALA4395246 | F | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 17 | ALA4393689 | cell-based format | Scientific Literature | |
| 6. | ALA4395247 | F | Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 17 | ALA4393689 | cell-based format | Scientific Literature | |
| 7. | ALA4395248 | F | Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 17 | ALA4393689 | cell-based format | Scientific Literature | |
| 8. | ALA4395249 | F | Potency index, ratio of IC50 of BTP to ratio of IC50 of compound for antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 9. | ALA4395250 | F | Potency index, ratio of IC50 of BTP to ratio of IC50 of compound for antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 10. | ALA4395251 | F | Potency index, ratio of IC50 of BTP to ratio of IC50 of compound for antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 11. | ALA4395252 | F | Potency index, ratio of IC50 of BTP to ratio of IC50 of compound for antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 12. | ALA4395253 | A | Cytotoxicity against human MCF10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA4393689 | cell-based format | Scientific Literature | |
| 13. | ALA4395254 | A | Cytotoxicity against human LO2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA4393689 | cell-based format | Scientific Literature | |
| 14. | ALA4395255 | T | Selectivity index, ratio of IC50 for human MCF10A cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 2 | ALA4393689 | assay format | Scientific Literature | |
| 15. | ALA4395256 | T | Selectivity index, ratio of IC50 for human L02 cells to IC50 for human HepG2 cells | Homo sapiens | 2 | ALA4393689 | assay format | Scientific Literature | |
| 16. | ALA4395257 | F | Inhibition of colony formation in human MDA-MB-231 cells assessed as reduction in cell proliferation at 1 uM treated for 24 hrs and measured after 10 to 14 days by crystal violet staining based assay | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 17. | ALA4395258 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 1.0%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 18. | ALA4395259 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 1 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 0.8%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 19. | ALA4395260 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 2 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 95.1%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature | |
| 20. | ALA4395261 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 2 uM incubated for 24 hrs by annexinV-FITC and propidium iodide staining based flow cytometric analysis (Rvb = 3.2%) | Homo sapiens | 1 | ALA4393689 | cell-based format | Scientific Literature |
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