| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4407207 | B | Inhibition of ovine COX2 using arachidonic acid as substrate by enzyme immunoassay | Ovis aries | 1 | single protein format | Scientific Literature | ||
| 2. | ALA5258298 | B | Inhibition of ovine COX-2 assessed as reduction in PGF2alpha production by enzyme immunoassay | Ovis aries | 1 | single protein format | Scientific Literature | ||
| 3. | ALA5258299 | B | Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with compound for 5 mins followed by substrate addition and measured after 2 mins by fluorescence spectrum analysis | Ovis aries | 3 | single protein format | Scientific Literature | ||
| 4. | ALA5258300 | B | Inhibition of recombinant human COX-2 using arachidonic acid as substrate preincubated with compound for 5 mins followed by substrate addition and measured after 2 mins by fluorescence spectrum analysis | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA5258301 | B | Selectivity index, ratio of IC50 for inhibition of ovine COX-1 to IC50 for inhibition of recombinant human COX-2 | 3 | assay format | Scientific Literature | |||
| 6. | ALA5258302 | T | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell survival at 10 uM incubated for 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5258303 | T | Cytotoxicity against human L02 cells assessed as reduction in cell survival at 10 uM incubated for 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5258304 | T | Cytotoxicity against mouse L929 cells assessed as reduction in cell survival at 10 uM incubated for 24 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5258305 | T | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell survival upto 50 uM incubated for 48 to 72 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5258306 | T | Cytotoxicity against human L02 cells assessed as reduction in cell survival upto 50 uM incubated for 48 to 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5258307 | T | Cytotoxicity against mouse L929 cells assessed as reduction in cell survival upto 50 uM incubated for 48 to 72 hrs by MTT assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5258308 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced iNOS protein expression incubated for 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5258309 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced COX-2 protein expression incubated for 24 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5258310 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced NO production incubated for 24 hrs by Griess reagent based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5258311 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced TNF-alpha production incubated for 24 hrs by ELISA analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5258312 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced IL-6 production incubated for 24 hrs by ELISA analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5258313 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as decrease in LPS-induced IL-1beta production incubated for 24 hrs by ELISA analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5258314 | B | Inhibition of COX-2 in mouse RAW264.7 cells assessed as suppression of LPS-induced PGE2 production at 2 to 30 uM incubated for 24 hrs by ELISA analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5258315 | B | Inhibition of NF-kappaB phosphorylation in LPS-stimulated mouse RAW264.7 cells at 2 to 30 uM preincubated with compound for 1 hrs followed by LPS-stimulation and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5258316 | F | Effect of NF-kappaB protein level in LPS-stimulated mouse RAW264.7 cells at 2 to 30 uM preincubated with compound for 1 hrs followed by LPS-stimulation and measured after 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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