| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4434026 | B | Binding affinity to d(CTG) T-T DNA sequence (unknown origin) assessed as mole fraction of compound required to show 2:1 stoichiometry for compound-DNA complex at 50 uM by Job's plot analysis | Not specified | 1 | assay format | Scientific Literature | ||
| 2. | ALA4434027 | B | Binding affinity to d(CTG) T-T 2 DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 1 | assay format | Scientific Literature | ||
| 3. | ALA4434032 | B | Binding affinity to d(CTG) duplex DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 4 | assay format | Scientific Literature | ||
| 4. | ALA4434033 | B | Binding affinity to d(CTG) T-T DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 4 | assay format | Scientific Literature | ||
| 5. | ALA4434034 | B | Binding affinity to d(CTG) A-A DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 3 | assay format | Scientific Literature | ||
| 6. | ALA4434035 | B | Binding affinity to d(CTG) C-C DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 4 | assay format | Scientific Literature | ||
| 7. | ALA4434036 | B | Binding affinity to d(CTG) U-U DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 4 | assay format | Scientific Literature | ||
| 8. | ALA4434037 | B | Binding affinity to d(CTG) T-T 3 DNA sequence (unknown origin) assessed as equilibrium dissociation constant by isothermal titration method | Not specified | 1 | assay format | Scientific Literature | ||
| 9. | ALA4434038 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 25 uM after 72 hrs by SRB assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4434041 | B | Inhibition of d(CTG.CAG)74 DNA sequence (unknown origin) transcription at 25 uM pre-incubated for 3 hrs followed by addition of T7 polymerase and measured after 1.5 hrs by PAGE analysis | Not specified | 4 | assay format | Scientific Literature | ||
| 11. | ALA4434044 | B | Inhibition of random DNA sequence (unknown origin) transcription at 100 uM pre-incubated for 3 hrs followed by addition of T7 polymerase and measured after 1.5 hrs by PAGE analysis | Not specified | 2 | nucleic acid format | Scientific Literature | ||
| 12. | ALA4434047 | B | Binding affinity to d(CTG) T-T DNA sequence (unknown origin) assessed as mole fraction of compound required to show 1:1 stoichiometry for compound-DNA complex at 50 uM by Job's plot analysis | Not specified | 1 | assay format | Scientific Literature | ||
| 13. | ALA4434048 | B | Binding affinity to d(CTG) T-T DNA sequence (unknown origin) assessed as mole fraction of compound required to show 1.3:1 stoichiometry for compound-DNA complex at 50 uM by Job's plot analysis | Not specified | 1 | assay format | Scientific Literature | ||
| 14. | ALA4434049 | B | Binding affinity to d(CTG) T-T 3 DNA sequence (unknown origin) assessed as binding constant by isothermal titration method | Not specified | 1 | assay format | Scientific Literature | ||
| 15. | ALA4434050 | B | Binding affinity to d(CTG) T-T 2 DNA sequence (unknown origin) assessed as binding constant by isothermal titration method | Not specified | 1 | assay format | Scientific Literature | ||
| 16. | ALA4434051 | B | Displacement of ethidium from d(CTG)2 DNA sequence (unknown origin) and measured by fluorescence method relative to NC | Not specified | 1 | assay format | Scientific Literature | ||
| 17. | ALA4434052 | B | Potency index, ratio of transcription inhibition of NC to transcription inhibition of compounds for d(CTG.CAG)74 DNA sequence by PAGE analysis | Not specified | 3 | assay format | Scientific Literature | ||
| 18. | ALA4434053 | A | Selectivity ratio of cytotoxicity of compound to cytotoxicity of NC for human HeLa cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4434054 | B | Selectivity ratio of transcription inhibition of random DNA sequence (unknown origin) to transcription inhibition of d(CTG.CAG)74 DNA sequence (unknown origin) by PAGE analysis | Not specified | 4 | assay format | Scientific Literature |
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