| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4336772 | B | Inhibition of hippo signalling protein in human A549 cells cotransfected with CTGF promoter-driven firefly luciferase and CMV promoter-driven renilla luciferase gene incubated for 24 hrs by dual-luciferase gene assay | Homo sapiens | 2 | ALA4334471 | cell-based format | Scientific Literature | |
| 2. | ALA4336774 | B | Inhibition of hippo signalling protein in human A549 cells cotransfected with CTGF promoter-driven firefly luciferase and CMV promoter-driven renilla luciferase gene assessed as reduction in CTGF expression at 10 uM incubated for 24 hrs by dual-luciferase gene assay relative to control | Homo sapiens | 29 | ALA4334471 | cell-based format | Scientific Literature | |
| 3. | ALA4336775 | F | Upregulation of CYR61 in human A549 cells incubated for 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | ALA4334471 | cell-based format | Scientific Literature | |
| 4. | ALA4336776 | B | Induction of YAP nuclear translocation in human A549 cells at 10 uM incubated for 8 hrs by immunofluorescence based confocal microscopy | Homo sapiens | 2 | ALA4334471 | cell-based format | Scientific Literature | |
| 5. | ALA4336777 | B | Inhibition of human AAK1 assessed as residual activity at 10 uM using peptide as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 6. | ALA4336778 | B | Inhibition of human ABL1 (27 to end residues) at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 7. | ALA4336779 | B | Inhibition of mouse ABL1 L782P/G784R/W785L/L786V mutant (27 to end residues) at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Mus musculus | 1 | ALA4334471 | assay format | Scientific Literature | |
| 8. | ALA4336780 | B | Inhibition of human ABL1 H396P mutant (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 9. | ALA4336781 | B | Inhibition of human ABL1 M351T mutant (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 10. | ALA4336782 | B | Inhibition of human ABL1 Q252H mutant (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 11. | ALA4336783 | B | Inhibition of human ABL1 T315I mutant (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 12. | ALA4336784 | B | Inhibition of human ABL1 Y253F mutant (27 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 13. | ALA4336785 | B | Inhibition of human ACK1 (1 to 389 residues) assessed as residual activity at 10 uM using EFPIYDFLPAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 14. | ALA4336786 | B | Inhibition of human ACTR2 (162 to end residues) assessed as residual activity at 10 uM using casein as substrate incubated for 120 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 15. | ALA4336787 | B | Inhibition of human ALK (1058 to end residues) assessed as residual activity at 10 uM using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 16. | ALA4336788 | B | Inhibition of recombinant human ALK1 (142 to end residues) assessed as residual activity at 10 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 17. | ALA4336789 | B | Inhibition of human ALK2 (147 to end residues) assessed as residual activity at 10 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 18. | ALA4336790 | B | Inhibition of human ALK4 (150 to end residues) assessed as residual activity at 10 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 19. | ALA4336791 | B | Inhibition of human ALK6 (148 to end residues) assessed as residual activity at 10 uM using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature | |
| 20. | ALA4336792 | B | Inhibition of human Arg (38 to end residues) assessed as residual activity at 10 uM using EAIYAAPFAKKK as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counting based radiometry assay relative to control | Homo sapiens | 1 | ALA4334471 | single protein format | Scientific Literature |
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