# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4423741 | B | Allosteric modulation of rat GluN2A expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
2. | ALA4423742 | B | Allosteric modulation of rat GluN2B expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
3. | ALA4423743 | B | Allosteric modulation of rat GluN2C expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
4. | ALA4423744 | B | Allosteric modulation of rat GluN2D expressed in Xenopus laevis oocytes assessed as L-glutamate/glycine-induced current response at 100 uM at holding potential -60 mV by two-electrode voltage clamp method relative to L-glutamate/glycine | Rattus norvegicus | 45 | ALA4422636 | cell-based format | Scientific Literature | |
5. | ALA4423749 | B | Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of 300 uM glutamate/glycine-induced current response at 30 uM at -60 mV holding potential by two-electrode voltage clamp method | Rattus norvegicus | 1 | ALA4422636 | cell-based format | Scientific Literature | |
6. | ALA4423750 | B | Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of 10 uM glutamate/glycine-induced current response at 30 uM at -60 mV holding potential by two-electrode voltage clamp method | Rattus norvegicus | 1 | ALA4422636 | cell-based format | Scientific Literature | |
7. | ALA4423751 | P | Solubility of the compound at 100 uM | 45 | ALA4422636 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4423760 | B | Negative allosteric modulation of rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
9. | ALA4423761 | B | Negative allosteric modulation of rat GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to untreated control | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
10. | ALA4423762 | B | Negative allosteric modulation of rat GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
11. | ALA4423763 | B | Negative allosteric modulation of rat GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to untreated control | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
12. | ALA4423764 | B | Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
13. | ALA4423765 | B | Negative allosteric modulation of rat GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to untreated control | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
14. | ALA4423766 | B | Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature | |
15. | ALA4423767 | B | Negative allosteric modulation of rat GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as inhibition of L-glutamate/glycine-induced current response at holding potential -60 mV by two-electrode voltage clamp method relative to untreated control | Rattus norvegicus | 5 | ALA4422636 | cell-based format | Scientific Literature |