| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4401249 | B | Inhibition of CMFDA binding to human N-terminal 6x-His-tagged GSTO1-1 preincubated for 30 mins followed by CMFDA addition and measured after 30 mins by in-gel fluorescence binding assay | Homo sapiens | 44 | single protein format | Scientific Literature | ||
| 2. | ALA4401250 | F | Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 3. | ALA4401251 | F | Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
| 4. | ALA4404678 | B | Inhibition of recombinant GSTO1-1 (unknown origin) expressed in Escherichia coli using S-(4-nitrophenacyl)glutathione as substrate preincubated for 2 mins followed by substrate addition by 4-NPG assay | Homo sapiens | 33 | assay format | Scientific Literature | ||
| 5. | ALA4404682 | B | Inhibition of GSTO1-1 in mouse bone marrow derived macrophage cells assessed as reduction in LPS-induced IL-1beta release by measuring IL1 beta level at 5 uM pretreated with LPS for 3 hrs followed by compound addition and measured after 1 hr by ELISA relative to control | Mus musculus | 11 | assay format | Scientific Literature |
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