| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4384228 | F | Antiparasitic activity against Giardia lamblia WB trophozoites after 24 to 48 hrs by CellTiter-Glo luminescent cell viability assay | Giardia intestinalis | 67 | ALA4382237 | organism-based format | Scientific Literature | |
| 2. | ALA4384229 | F | Antiparasitic activity against Entamoeba histolytica HM-1:IMSS trophozoites after 24 to 48 hrs by CellTiter-Glo luminescent cell viability assay | Entamoeba histolytica | 50 | ALA4382237 | organism-based format | Scientific Literature | |
| 3. | ALA4384230 | F | Antibacterial activity against Clostridium difficile 630 ATCC BAA-1382 by broth microdilution assay | Clostridioides difficile | 23 | ALA4382237 | organism-based format | Scientific Literature | |
| 4. | ALA4384231 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv after 5 days under normoxic condition by resazurin dye-based fluorescence assay | Mycobacterium tuberculosis | 66 | ALA4382237 | organism-based format | Scientific Literature | |
| 5. | ALA4384233 | F | Antibacterial activity against non-replicating Mycobacterium tuberculosis H37Rv after 5 days under hypoxic condition by resazurin dye-based fluorescence assay | Mycobacterium tuberculosis | 64 | ALA4382237 | organism-based format | Scientific Literature | |
| 6. | ALA4384238 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 4330 by broth microdilution assay | Staphylococcus aureus | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 7. | ALA4384239 | F | Antibacterial activity against Escherichia coli ATCC 25922 by broth microdilution assay | Escherichia coli | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 8. | ALA4384240 | F | Antibacterial activity against Klebsiella pneumoniae 700603 by broth microdilution assay | Klebsiella pneumoniae | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 9. | ALA4384241 | F | Antibacterial activity against Acinetobacter baumannii ATCC 19606 by broth microdilution assay | Acinetobacter baumannii | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 10. | ALA4384242 | F | Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 by broth microdilution assay | Pseudomonas aeruginosa | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 11. | ALA4384243 | F | Antifungal activity against Candida albicans ATCC 90028 by broth microdilution assay | Candida albicans | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 12. | ALA4384244 | F | Antifungal activity against Cryptococcus neoformans H99 ATCC 20882 by broth microdilution assay | Cryptococcus neoformans | 22 | ALA4382237 | organism-based format | Scientific Literature | |
| 13. | ALA4384245 | A | Cytotoxicity against HEK293 cells after 24 hrs by resazurin dye-based fluorescence assay | Homo sapiens | 24 | ALA4382237 | cell-based format | Scientific Literature | |
| 14. | ALA4384246 | A | Cytotoxicity against human HepG2 cells after 24 hrs by resazurin dye-based fluorescence assay | Homo sapiens | 24 | ALA4382237 | cell-based format | Scientific Literature | |
| 15. | ALA4384249 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining at 3 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 11 | ALA4382237 | microsome format | Scientific Literature | |
| 16. | ALA4384250 | A | Metabolic stability in CD-1 mouse liver microsomes assessed as parent compound remaining at 3 uM after 2 hrs by LC-MS/MS analysis | Mus musculus | 11 | ALA4382237 | microsome format | Scientific Literature | |
| 17. | ALA4384251 | A | Metabolic stability in human plasma assessed as parent compound remaining at 3 uM after 2 hrs by LC-MS/MS analysis | Homo sapiens | 12 | ALA4382237 | cell-free format | Scientific Literature | |
| 18. | ALA4384252 | A | Metabolic stability in CD-1 mouse plasma assessed as parent compound remaining at 3 uM after 2 hrs by LC-MS/MS analysis | Mus musculus | 12 | ALA4382237 | cell-free format | Scientific Literature | |
| 19. | ALA4384253 | A | Protein binding in human plasma at 5 uM after 30 mins by LC-MS/MS analysis based ultrafiltration method | Homo sapiens | 12 | ALA4382237 | cell-free format | Scientific Literature | |
| 20. | ALA4384254 | A | Apparent permeability across apical to basolateral side in human Caco2 cells at 2 uM after 2 hrs by lucifer yellow dye-based LC-MS/MS analysis | Homo sapiens | 7 | ALA4382237 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!