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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA4355751 A Apparent permeability in pig LLC-PK1 cells transfected with MDR1 Sus scrofa 25 cell-based format Scientific Literature 2. ALA4355753 A Fraction unbound in human plasma at 2.5 uM by equilibrium dialysis Homo sapiens 11 cell-free format Scientific Literature 3. ALA4355754 B Inhibition of recombinant human OGA Homo sapiens 48 single protein format Scientific Literature 4. ALA4355755 B Inhibition of OGA in rat PC12 cells assessed as OGlcNAcylated protein level incubated for 24 hrs by ELISA Rattus norvegicus 25 cell-based format Scientific Literature 5. ALA4355756 B Inhibition of human beta hexosaminidase assessed as inhibitory constant using 4-methylumbelliferyl N-acetyl-beta-D-glucosaminide dihydrate as substrate measured every 60 sec for 45 mins by fluorescence spectrophotometry Homo sapiens 41 single protein format Scientific Literature 6. ALA4355757 A Fraction unbound in Wistar Han rat plasma at 2.5 uM by equilibrium dialysis Rattus norvegicus 11 cell-free format Scientific Literature 7. ALA4355759 A AUCN in Wistar Han rat at 3 mg/kg, po Rattus norvegicus 14 organism-based format Scientific Literature 8. ALA4355760 A Clearance in Wistar Han rat at 2 mg/kg, iv Rattus norvegicus 18 organism-based format Scientific Literature 9. ALA4355765 A Volume of distribution at steady state in Wistar Han rat at 2 mg/kg, iv or 3 mg/kg, po Rattus norvegicus 12 organism-based format Scientific Literature 10. ALA4355768 A Oral bioavailability in Wistar Han rat at 3 mg/kg Rattus norvegicus 14 organism-based format Scientific Literature 11. ALA4355769 F Elevation of O-protein in rat brain at 3 mg/kg, po measured after 8 hrs relative to control Rattus norvegicus 11 organism-based format Scientific Literature 12. ALA4355770 F Elevation of O-protein in rat brain at 3 mg/kg, po measured after 24 hrs relative to control Rattus norvegicus 7 organism-based format Scientific Literature 13. ALA4355771 A Drug uptake in rat brain at 3 mg/kg, po measured after 8 hrs Rattus norvegicus 11 organism-based format Scientific Literature 14. ALA4355772 A Drug uptake in rat brain at 3 mg/kg, po measured after 24 hrs Rattus norvegicus 7 organism-based format Scientific Literature 15. ALA4355773 A Ratio of drug uptake in rat brain to plasma at 3 mg/kg, po measured after 8 hrs Rattus norvegicus 11 organism-based format Scientific Literature 16. ALA4355774 A Ratio of drug uptake in rat brain to plasma at 3 mg/kg, po measured after 24 hrs Rattus norvegicus 7 organism-based format Scientific Literature