# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4413796 | B | Inhibition of full length human APE1 assessed as reduction in endonuclease activity by measuring DNA cleavage of abasic sites using 6-FAM labelled two annealed oligonucleotides as AP site mimic substrate by fluorescence-based assay | Homo sapiens | 22 | ALA4411319 | single protein format | Scientific Literature | |
2. | ALA4413797 | F | Cytotoxicity against human Pa02C cells after 48 hrs by Alamar Blue-based assay | Homo sapiens | 18 | ALA4411319 | cell-based format | Scientific Literature | |
3. | ALA4413798 | B | Inhibition of APE1 in human ST8814 cells assessed as effect on MMS-induced DNA damage by measuring tail DNA level at 100 uM after 1 hr in presence of MMS by comet assay (Rvb = 16%) | Homo sapiens | 7 | ALA4411319 | cell-based format | Scientific Literature | |
4. | ALA4413799 | F | Induction of DNA damage in human ST8814 cells measuring tail DNA level at 100 uM after 1 hr in presence of MMS by comet assay (Rvb = 16%) | Homo sapiens | 7 | ALA4411319 | cell-based format | Scientific Literature |