# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4357635 | Binding | Inhibition of recombinant human SphK2 transfected in HEK293T cells at 0.3 uM using D-erythro-sphingosine as substrate incubated for 20 mins in presence of [gamma32P]-ATP by liquid scintillation counting method relative to control | Homo sapiens | 23 | ALA4354840 | cell-based format | Scientific Literature | |
2. | ALA4357637 | Binding | Inhibition of human SphK1 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth measured after 24 hrs | Homo sapiens | 7 | ALA4354840 | assay format | Scientific Literature | |
3. | ALA4357638 | Binding | Inhibition of human SphK2 expressed in Saccharomyces cerevisiae KYA1 assessed as yeast growth measured after 24 hrs | Homo sapiens | 7 | ALA4354840 | assay format | Scientific Literature | |
4. | ALA4357647 | ADME | Toxicity against Saccharomyces cerevisiae KYA1 assessed as cell death at >3 uM incubated for 24 to 48 hrs | Saccharomyces cerevisiae | 7 | ALA4354840 | organism-based format | Scientific Literature |