# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4340581 | F | Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay | Homo sapiens | 26 | ALA4340501 | cell-based format | Scientific Literature | |
2. | ALA4340582 | F | Agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay | Homo sapiens | 21 | ALA4340501 | cell-based format | Scientific Literature | |
3. | ALA4340583 | B | Selectivity ratio of compound effect for agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells to compound effect for agonist activity at human beta1 adrenergic receptor expressed in HEK293 cells | Homo sapiens | 21 | ALA4340501 | cell-based format | Scientific Literature | |
4. | ALA4340584 | F | Intrinsic activity at human beta2 adrenergic receptor in HEK293 cells assessed as increase in cAMP accumulation after 60 mins by HTRF assay relative to isoprenaline | Homo sapiens | 7 | ALA4340501 | cell-based format | Scientific Literature | |
5. | ALA4340585 | B | Agonist activity at beta2 adrenergic receptor in Dunkin-Hartley guinea pig trachea assessed as reduction in histamine-induced muscle contraction relative to control | Cavia porcellus | 5 | ALA4340501 | tissue-based format | Scientific Literature | |
6. | ALA4340586 | B | Agonist activity at beta2 adrenergic receptor in Dunkin-Hartley guinea pig trachea assessed as reduction in histamine-induced muscle contraction | Cavia porcellus | 5 | ALA4340501 | tissue-based format | Scientific Literature | |
7. | ALA4340587 | B | Intrinsic activity at beta2 adrenergic receptor in Dunkin-Hartley guinea pig trachea assessed as reduction in histamine-induced muscle contraction relative to isoprenaline | Cavia porcellus | 4 | ALA4340501 | tissue-based format | Scientific Literature | |
8. | ALA4340588 | B | Agonist activity at beta2 adrenergic receptor in Dunkin-Hartley guinea pig trachea assessed as reduction in histamine-induced muscle contraction by measuring onset time | Cavia porcellus | 4 | ALA4340501 | tissue-based format | Scientific Literature | |
9. | ALA4340589 | B | Agonist activity at beta2 adrenergic receptor in Dunkin-Hartley guinea pig trachea assessed as reduction in histamine-induced muscle contraction by measuring time of action | Cavia porcellus | 3 | ALA4340501 | tissue-based format | Scientific Literature |