# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4400858 | Functional | Antileishmanial activity against Leishmania donovani MHOM/SD/001S-2D promastigotes transformed from splenic cultures of infected Chester Beatty hamster measured after 48 hrs by CellTiter-Glo luminescent cell viability assay | Leishmania donovani | 1 | ALA4400515 | organism-based format | Scientific Literature | |
2. | ALA4400859 | Functional | Antileishmanial activity against Leishmania donovani MHOM/SD/001S-2D promastigotes infected in Chester Beatty hamster macrophage measured after 48 hrs by CellTiter-Glo luminescent cell viability assay | Leishmania donovani | 1 | ALA4400515 | organism-based format | Scientific Literature | |
3. | ALA4400860 | Functional | Antileishmanial activity against promastigote stage of Leishmania major MHOM/IL/81/Friedlin transformed from lymph node cultures of infected Balb/c mouse measured after 48 hrs by luminometry | Leishmania major | 1 | ALA4400515 | organism-based format | Scientific Literature | |
4. | ALA4400861 | Functional | Antileishmanial activity against promastigote stage of Leishmania major MHOM/IL/81/Friedlin infected in Balb/c mouse macrophage measured after 48 hrs by luminometry | Leishmania major | 1 | ALA4400515 | organism-based format | Scientific Literature | |
5. | ALA4400863 | Functional | Antimalarial activity against Plasmodium vinckei petteri infected in IOPS OF1 mouse assessed as reduction in parasitemia administered once daily via sc for 4 days | Plasmodium vinckei petteri | 2 | ALA4400515 | organism-based format | Scientific Literature | |
6. | ALA4400864 | Functional | Antimalarial activity against Plasmodium vinckei petteri infected in IOPS OF1 mouse assessed as reduction in parasitemia at 10 mg/kg, sc administered once daily for 4 days relative to control | Plasmodium vinckei petteri | 1 | ALA4400515 | organism-based format | Scientific Literature | |
7. | ALA4400869 | Functional | Antiparasitic activity against Toxoplasma gondii infected in Scottish Blackface ewes assessed as mortality at 16.8 to 27.9 mg administered daily for 10 days prior to parasitic infection (Rvb = 55.2%) | Toxoplasma gondii | 1 | ALA4400515 | organism-based format | Scientific Literature | |
8. | ALA4400871 | Functional | Antiparasitic activity against Cryptosporidium parvum GP-60 subtype 2a A15G2RI infected in human HCT8 cells assessed as inhibition of parasite development at 0.144 uM measured 27 hrs post infection by qPCR analysis | Cryptosporidium parvum | 1 | ALA4400515 | organism-based format | Scientific Literature |