| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4345047 | B | Displacement of 2FAMInsP5 from recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells by fluorescence polarization assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA4345048 | B | Binding affinity to recombinant human N-terminal His-tagged SHIP2 (419 to 832 residues) expressed in Escherichia coli Rosetta2 (DE3) cells assessed as increase in release of phosphate at 100 uM incubated for 10 mins by phosphate release assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4345052 | B | Inhibition of recombinant human brain INPP5A expressed in Escherichia coli incubated for 10 mins by malachite green reagent based phosphate assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 4. | ALA5053561 | B | Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarization based displacement assay | Homo sapiens | 15 | single protein format | Scientific Literature |
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