# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4395391 | B | Binding affinity to G-quadruplex G2 DNA (unknown origin) assessed as increase in deltaTm at compound to DNA ratio of 10:1 by fluorescence thermal denaturation analysis | Not specified | 10 | nucleic acid format | Scientific Literature | ||
2. | ALA4395392 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 100 mM K+ by circular dichroism thermal denaturation analysis (Rvb= 52.6 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
3. | ALA4395393 | B | Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 150 mM Na+ by circular dichroism thermal denaturation analysis (Rvb = 57.4 degC) | Not specified | 14 | nucleic acid format | Scientific Literature | ||
4. | ALA4395400 | B | Inhibition of telomerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 13 | subcellular format | Scientific Literature | ||
5. | ALA4395401 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at 6.25 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 12 | subcellular format | Scientific Literature | ||
6. | ALA4395404 | B | Inhibition of telomerase activity in human HeLa cell lysate at 10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 5 | subcellular format | Scientific Literature | ||
7. | ALA4395415 | B | Inhibition of telomerase activity in human HeLa cell lysate at 0.625 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
8. | ALA4395419 | B | Inhibition of DNA polymerase activity in human HeLa cell lysate at <10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 2 | subcellular format | Scientific Literature | ||
9. | ALA4395420 | B | Inhibition of telomerase activity in human HeLa cell lysate at <10 uM in presence of [32P]-labeled template primer by TRAP assay | Homo sapiens | 2 | subcellular format | Scientific Literature |