# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4338134 | Binding | Inhibition of recombinant MTHFD2 (unknown origin) using THF as substrate incubated for 30 mins in presence of NAD | Homo sapiens | 23 | ALA4334513 | single protein format | Scientific Literature | |
2. | ALA4338135 | Binding | Inhibition of recombinant MTHFD1 (unknown origin) using THF as substrate incubated for 30 mins in presence of NAD | Homo sapiens | 23 | ALA4334513 | single protein format | Scientific Literature | |
3. | ALA4338136 | Binding | Selectivity ratio of IC50 for inhibition of recombinant MTHFD1 (unknown origin) to IC50 for inhibition of recombinant MTHFD2 (unknown origin) | Homo sapiens | 23 | ALA4334513 | assay format | Scientific Literature | |
4. | ALA4338139 | Physicochemical | Lipophilicity, logP of compound | 13 | ALA4334513 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4338140 | Functional | Antiproliferative activity against human MDA-MB-231-luc-D3H2LN cells assessed as inhibition of growth after 3 days by CellTiter Glo assay | Homo sapiens | 13 | ALA4334513 | assay format | Scientific Literature |