# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4388072 | ADME | Cytotoxicity against mouse MIN6 cells assessed as reduction in cell viability up to 200 uM incubated for 24 hrs by MTT assay | Mus musculus | 16 | ALA4387705 | cell-based format | Scientific Literature | |
2. | ALA4388073 | ADME | Cytotoxicity against mouse MIN6 cells assessed as cell viability at 400 uM incubated for 24 hrs by MTT assay | Mus musculus | 16 | ALA4387705 | cell-based format | Scientific Literature | |
3. | ALA4388074 | Functional | Antidiabetic activity in mouse MIN6 cells after 35 passages assessed as increase in insulin secretion at 100 uM in presence of 25 mM glucose by ELISA relative to control | Mus musculus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
4. | ALA4388075 | Functional | Antidiabetic activity in mouse MIN6 cells after 83 passages assessed as increase in insulin secretion at 100 uM in presence of 25 mM glucose by ELISA relative to control | Mus musculus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
5. | ALA4388080 | Binding | Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH at 50 uM preincubated for 5 mins followed by substrate addition and measured after 30 mins at 2 mins interval by spectrophotometry relative to control | Homo sapiens | 18 | ALA4387705 | assay format | Scientific Literature | |
6. | ALA4388081 | Binding | Inhibition of human recombinant ALR2 expressed in Escherichia coli using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured after 30 mins at 2 mins interval by spectrophotometry relative to control | Homo sapiens | 18 | ALA4387705 | assay format | Scientific Literature | |
7. | ALA4388082 | Binding | Inhibition of rat kidney ALR1 using DL-glyceraldehyde as substrate and NADPH at 50 uM preincubated for 5 mins followed by substrate addition and measured for 30 mins at 2 mins interval by spectrophotometry relative to control | Rattus norvegicus | 18 | ALA4387705 | single protein format | Scientific Literature | |
8. | ALA4388083 | Binding | Inhibition of rat kidney ALR1 using DL-glyceraldehyde as substrate and NADPH preincubated for 5 mins followed by substrate addition and measured for 30 mins at 2 mins interval by spectrophotometry relative to control | Rattus norvegicus | 18 | ALA4387705 | single protein format | Scientific Literature | |
9. | ALA4388085 | Binding | Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation at 0.1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
10. | ALA4388086 | Binding | Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation at 1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
11. | ALA4388087 | Binding | Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation at 10 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
12. | ALA4388088 | Binding | Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation at 50 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
13. | ALA4388089 | Binding | Inhibition of ALR2 in rat erythrocytes assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | cell-based format | Scientific Literature | |
14. | ALA4388090 | Binding | Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation at 0.1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
15. | ALA4388091 | Binding | Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation at 1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
16. | ALA4388092 | Binding | Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation at 10 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
17. | ALA4388093 | Binding | Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation at 50 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
18. | ALA4388094 | Binding | Inhibition of ALR2 in rat sciatic nerve assessed as reduction in sorbitol accumulation incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
19. | ALA4388095 | Binding | Inhibition of ALR2 in rat lens assessed as reduction in sorbitol accumulation at 0.1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature | |
20. | ALA4388096 | Binding | Inhibition of ALR2 in rat lens assessed as reduction in sorbitol accumulation at 1 uM incubated for 3 hrs in presence of 28 mM glucose by gas chromatographic analysis relative to control | Rattus norvegicus | 17 | ALA4387705 | assay format | Scientific Literature |