# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4432598 | A | Cytotoxicity against mouse Shh Light2 cells up to 150 uM after 40 hrs by MTT assay | Mus musculus | 3 | ALA4431354 | cell-based format | Scientific Literature | |
2. | ALA4432600 | F | Effect on Smo expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
3. | ALA4432601 | F | Effect on Ptch1 expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
4. | ALA4432602 | F | Effect on SuFu expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
5. | ALA4432603 | F | Effect on SHH expression in mouse Shh Light2 cells at 75 to 100 uM after 24 hrs by Western blot analysis | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
6. | ALA4432604 | B | Inhibition of Shh-N-induced Gli1 (unknown origin) expressed in mouse Shh Light2 cells assessed as Gli1-mediated mediated transcription at 50 uM incubated for 30 hrs by firefly luciferase assay | Homo sapiens | 4 | ALA4431354 | cell-based format | Scientific Literature | |
7. | ALA4432606 | B | Inhibition of Gli1 (unknown origin) expression in mouse Shh Light2 cells at 1 to 100 uM by Western blot analysis | Homo sapiens | 2 | ALA4431354 | cell-based format | Scientific Literature | |
8. | ALA4432611 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G0/G1 phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 86.2%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
9. | ALA4432612 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G2/M phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 6.7%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
10. | ALA4432613 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at S phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.6%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
11. | ALA4432614 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at subG0 phase at 30 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.4%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
12. | ALA4432615 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G0/G1 phase at 100 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 86.2%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
13. | ALA4432616 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at G2/M phase at 100 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 6.7%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
14. | ALA4432617 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at S phase at 100 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.6%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature | |
15. | ALA4432618 | F | Cell cycle arrest in mouse Shh Light2 cells assessed as accumulation at subG0 phase at 100 uM after 30 to 48 hrs by propidium iodide staining-based flow cytometry (Rvb = 3.4%) | Mus musculus | 1 | ALA4431354 | cell-based format | Scientific Literature |