# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4350329 | Binding | Negative allosteric modulation of rat mGlu3R expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux | Rattus norvegicus | 19 | ALA4346754 | cell-based format | Scientific Literature | |
2. | ALA4350330 | Functional | Negative allosteric modulation of rat mGlu3R expressed in HEK293 cells co-expressing Galpha15 assessed as decrease in glutamate-induced calcium mobilization relative to glutamate | Rattus norvegicus | 20 | ALA4346754 | cell-based format | Scientific Literature | |
3. | ALA4350331 | ADME | Fraction unbound in rat plasma | Rattus norvegicus | 3 | ALA4346754 | cell-free format | Scientific Literature | |
4. | ALA4350332 | ADME | Fraction unbound in rat brain homogenate | Rattus norvegicus | 3 | ALA4346754 | tissue-based format | Scientific Literature | |
5. | ALA4350333 | ADME | Permeability coefficient, Kp in rat brain | Rattus norvegicus | 3 | ALA4346754 | tissue-based format | Scientific Literature |