# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4395375 | Binding | Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 5 mins by Ellman's method | Electrophorus electricus | 10 | ALA4393694 | single protein format | Scientific Literature | |
2. | ALA4395376 | Binding | Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate pretreated for 5 mins followed by substrate addition measured after 5 mins by Ellman's method | Equus caballus | 10 | ALA4393694 | single protein format | Scientific Literature | |
3. | ALA4395377 | Binding | Selectivity index, ratio of IC50 for equine serum BChE to IC50 for electric eel AChE | 7 | ALA4393694 | assay format | Scientific Literature | ||
4. | ALA4395379 | Binding | Inhibition of self-mediated amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM incubated for 48 hrs by thioflavin-T fluorescence assay relative to control | Homo sapiens | 10 | ALA4393694 | single protein format | Scientific Literature | |
5. | ALA4395380 | Binding | Disaggregation of self-induced amyloid beta (1 to 42) (unknown origin) preformed fibrils measured after 24 hrs by ThT fluorescence assay relative to control | Homo sapiens | 9 | ALA4393694 | single protein format | Scientific Literature | |
6. | ALA4395387 | Functional | Antioxidant activity assessed as AAPH-induced radical scavenging activity by measuring trolox equivalents for oxygen radical absorbance capacity measured up to 80 mins by ORAC-FL assay | 10 | ALA4393694 | assay format | Scientific Literature |