# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4338441 | Binding | Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells at 10 uM using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay relative to control | Homo sapiens | 2 | ALA4334526 | cell-based format | Scientific Literature | |
2. | ALA4338442 | Binding | Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells at 10 uM ZMAL as substrate incubated for 90 mins by fluorescence assay relative to control | Homo sapiens | 18 | ALA4334526 | cell-based format | Scientific Literature | |
3. | ALA4338443 | Binding | Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells at 10 uM using Boc-Lys(epsilon-acetyl)-AMC as substrate incubated for 90 mins by fluorescence assay relative to control | Homo sapiens | 6 | ALA4334526 | cell-based format | Scientific Literature | |
4. | ALA4338444 | Binding | Inhibition of human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 20 | ALA4334526 | cell-based format | Scientific Literature | |
5. | ALA4338447 | Binding | Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using ZMAL as substrate incubated for 90 mins by fluorescence assay | Homo sapiens | 19 | ALA4334526 | cell-based format | Scientific Literature | |
6. | ALA4338450 | Functional | Cytotoxicity against human A2780 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay | Homo sapiens | 16 | ALA4334526 | cell-based format | Scientific Literature | |
7. | ALA4338451 | Functional | Cytotoxicity against human CAL27 cells assessed as reduction in cell survival measured after 72 hrs by MTT assay | Homo sapiens | 18 | ALA4334526 | cell-based format | Scientific Literature | |
8. | ALA4338453 | Binding | Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay | Homo sapiens | 18 | ALA4334526 | cell-based format | Scientific Literature | |
9. | ALA4338454 | Binding | Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition and measured after 3 hrs by fluorescence assay | Homo sapiens | 18 | ALA4334526 | cell-based format | Scientific Literature |