#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4333204	Binding	Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged Cul3 (unknown origin) expressed in baculovirus infected Sf9 insect cells measured after 1 hr by TR-FRET assay	Homo sapiens	102	ALA4330129	cell-based format	Scientific Literature
2.	ALA4333205	Binding	Binding affinity to FLAG/His-tagged Keap1 (unknown origin)/biotinylated full-length FLAG/His/Tev/Avi-tagged NRF2 (unknown origin) expressed in baculovirus infected Sf9 insect cells measured after 1 hr by TR-FRET assay	Homo sapiens	103	ALA4330129	cell-based format	Scientific Literature
3.	ALA4333206	Binding	Activation of Keap1/Cul3/Nrf2 in NHBE cells assessed as induction of HO-1 gene expression at 10 uM after 24 hrs by RT-PCR analysis relative to SFN	Homo sapiens	108	ALA4330129	cell-based format	Scientific Literature
4.	ALA4333207	Binding	Binding affinity to wild-type human N-terminal His6-tagged Keap1 (35 to 178 residues) expressed in baculovirus infected Sf9 insect cells assessed as cysteine-compound adduct formation at 15-fold molar excess measured after 1 hr by RP-LC/MS/MS analysis	Homo sapiens	2	ALA4330129	cell-based format	Scientific Literature
5.	ALA4333208	Binding	Binding affinity to human N-terminal His6-tagged Keap1 C151S mutant (35 to 182 residues) expressed in baculovirus infected Sf9 insect cells assessed as cysteine-compound adduct formation at 15-fold molar excess measured after 1 hr by RP-LC/MS/MS analysis	Homo sapiens	2	ALA4330129	cell-based format	Scientific Literature
6.	ALA4333209	Physicochemical	Kinetic solubility of the compound at pH 7.4 by CLND method		92	ALA4330129	small-molecule physicochemical format	Scientific Literature
7.	ALA4333210	Physicochemical	Lipophilicity, log D of the compound at pH 7.4 by chromatographic method		94	ALA4330129	small-molecule physicochemical format	Scientific Literature
8.	ALA4333211	Physicochemical	Solubility of the compound in FaSSIF at pH 6.5 using solid sample		1	ALA4330129	small-molecule physicochemical format	Scientific Literature
9.	ALA4333212	Physicochemical	Stability of the compound at 23 degC using crystalline solid sample measured >3 years by LC/MS analysis		1	ALA4330129	small-molecule physicochemical format	Scientific Literature
10.	ALA4333213	Physicochemical	Stability of the compound at 23 degC using crystalline solid sample measured >3 years by 1H-NMR analysis		1	ALA4330129	small-molecule physicochemical format	Scientific Literature
11.	ALA4333214	ADME	Apparent permeability across apical to basolateral side in MDCK-MDR1	Canis lupus familiaris	1	ALA4330129	cell-based format	Scientific Literature
12.	ALA4333215	ADME	Apparent permeability across basolateral to apical side in MDCK-MDR1	Canis lupus familiaris	1	ALA4330129	cell-based format	Scientific Literature
13.	ALA4333216	Binding	Activation of Keap1/Cul3/Nrf2 in human BEAS2B cells assessed as increase in NQO1 levels measured after 48 hrs	Homo sapiens	7	ALA4330129	cell-based format	Scientific Literature
14.	ALA4333217	Binding	Inhibition of Bach1-Mafk interaction (unknown origin) by luciferase reporter gene based enzyme fragment complementation assay	Homo sapiens	2	ALA4330129	protein format	Scientific Literature
15.	ALA4333218	Functional	Antioxidant activity in po dosed C57BL/6J mouse model of cigarette smoking-induced oxidative stress assessed as inhibition of neutrophil infiltration dosed 24 hrs prior to cigarette smoking followed by qd dosing with cigarette smoking for 3 days by Wright-Giemsa staining based hemocytometry	Mus musculus	1	ALA4330129	organism-based format	Scientific Literature
16.	ALA4333219	Functional	Antioxidant activity in C57BL/6J mouse model of cigarette smoking-induced oxidative stress assessed as inhibition of neutrophil infiltration at 0.1 to 100 umol/kg, po dosed 24 hrs prior to cigarette smoking followed by qd dosing with cigarette smoking for 3 days by Wright-Giemsa staining based hemocytometry	Mus musculus	1	ALA4330129	organism-based format	Scientific Literature
17.	ALA4333220	Functional	Antioxidant activity in C57BL/6J mouse model of cigarette smoking-induced oxidative stress assessed as inhibition of total cell infiltration at 0.1 to 100 umol/kg, po dosed 24 hrs prior to cigarette smoking followed by qd dosing with cigarette smoking for 3 days by Wright-Giemsa staining based hemocytometry	Mus musculus	1	ALA4330129	organism-based format	Scientific Literature
18.	ALA4333221	Functional	Antioxidant activity in C57BL/6J mouse model of cigarette smoking-induced oxidative stress assessed as inhibition of mononuclear cell infiltration at 0.1 to 100 umol/kg, po dosed 24 hrs prior to cigarette smoking followed by qd dosing with cigarette smoking for 3 days by Wright-Giemsa staining based hemocytometry	Mus musculus	1	ALA4330129	organism-based format	Scientific Literature
19.	ALA4333222	ADME	Drug metabolism in rat assessed as (2S)-2-amino-5-[[(1R)-2-(carboxymethylamino)-1-[3-[[2-(dimethylamino)-3,4-dioxo-cyclobuten-1-yl]-methyl-amino]propylcarbamothioylsulfanylmethyl]-2-oxo-ethyl]amino]-5-oxo-pentanoic acid formation at 2 mg/kg, po	Rattus norvegicus	1	ALA4330129	organism-based format	Scientific Literature
20.	ALA4333223	ADME	Drug metabolism in rat assessed as (2R)-2-acetamido-3-[3-[[2-(dimethylamino)-3,4-dioxo-cyclobuten-1-yl]-methyl-amino]propylcarbamothioylsulfanyl]propanoic acid formation at 2 mg/kg, po	Rattus norvegicus	1	ALA4330129	organism-based format	Scientific Literature