# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4394921 | Functional | Antiproliferative activity against human SMMC7721 cells assessed as reduction in cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 24 | ALA4393680 | cell-based format | Scientific Literature | |
2. | ALA4394922 | Binding | Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence method | Homo sapiens | 7 | ALA4393680 | cell-based format | Scientific Literature | |
3. | ALA4394923 | Functional | Antiproliferative activity against human A375 cells assessed as reduction in cell growth at 8 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
4. | ALA4394924 | Functional | Antiproliferative activity against human A375 cells assessed as reduction in cell growth at 2 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
5. | ALA4394925 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth at 8 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
6. | ALA4394926 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth at 2 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
7. | ALA4394927 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell growth at 8 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
8. | ALA4394928 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell growth at 2 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
9. | ALA4394929 | Functional | Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth at 8 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
10. | ALA4394930 | Functional | Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth at 2 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
11. | ALA4394931 | Functional | Antiproliferative activity against human SMMC7721 cells assessed as reduction in cell growth at 8 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
12. | ALA4394932 | Functional | Antiproliferative activity against human SMMC7721 cells assessed as reduction in cell growth at 2 uM incubated for 72 hrs by CCK-8 assay relative to control | Homo sapiens | 39 | ALA4393680 | cell-based format | Scientific Literature | |
13. | ALA4394933 | Functional | Antiproliferative activity against human A375 cells assessed as reduction in cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 24 | ALA4393680 | cell-based format | Scientific Literature | |
14. | ALA4394934 | Functional | Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 24 | ALA4393680 | cell-based format | Scientific Literature | |
15. | ALA4394935 | Functional | Antiproliferative activity against human A549 cells assessed as reduction in cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 24 | ALA4393680 | cell-based format | Scientific Literature | |
16. | ALA4394936 | Functional | Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 24 | ALA4393680 | cell-based format | Scientific Literature | |
17. | ALA4394937 | Binding | Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence method | Homo sapiens | 7 | ALA4393680 | cell-based format | Scientific Literature | |
18. | ALA4394938 | Binding | Inhibition of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS Green as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence method | Homo sapiens | 7 | ALA4393680 | cell-based format | Scientific Literature | |
19. | ALA4394939 | Binding | Selectivity ratio of IC50 for human recombinant His-tagged HDAC6 expressed in baculovirus infected insect cells to IC50 of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells | Homo sapiens | 7 | ALA4393680 | cell-based format | Scientific Literature | |
20. | ALA4394940 | Binding | Selectivity ratio of IC50 for human recombinant His-tagged HDAC6 expressed in baculovirus infected insect cells to IC50 of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells | Homo sapiens | 7 | ALA4393680 | cell-based format | Scientific Literature |