# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4336043 | Binding | Agonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | ALA4334454 | cell-based format | Scientific Literature | |
2. | ALA4336044 | Binding | Agonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | ALA4334454 | cell-based format | Scientific Literature | |
3. | ALA4336045 | Binding | Agonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as increase in calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 4 | ALA4334454 | cell-based format | Scientific Literature | |
4. | ALA4336046 | Binding | Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature | |
5. | ALA4336047 | Binding | Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature | |
6. | ALA4336048 | Binding | Antagonist activity at human AChR alpha7 transfected in rat GH3 cells assessed as decrease in epibatidine-induced calcium influx incubated for 1 hr by fluo-4 dye based assay | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature | |
7. | ALA4336049 | Binding | Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature | |
8. | ALA4336050 | Binding | Antagonist activity at human AChR alpha3beta4 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 1 | ALA4334454 | cell-based format | Scientific Literature | |
9. | ALA4336053 | Binding | Antagonist activity at human AChR alpha4beta2 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature | |
10. | ALA4336054 | Binding | Antagonist activity at human AChR alpha7 transfected in human HEK293 cells assessed as decrease in epibatidine-induced calcium influx at 10 to 100 uM incubated for 1 hr by fluo-4 dye based assay relative to control | Homo sapiens | 3 | ALA4334454 | cell-based format | Scientific Literature |