| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4398935 | F | Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 27 | ALA4396906 | cell-based format | Scientific Literature | |
| 2. | ALA4398936 | F | Antiproliferative activity against human SW480 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 27 | ALA4396906 | cell-based format | Scientific Literature | |
| 3. | ALA4398937 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 27 | ALA4396906 | cell-based format | Scientific Literature | |
| 4. | ALA4398938 | A | Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 27 | ALA4396906 | cell-based format | Scientific Literature | |
| 5. | ALA4398939 | B | Inhibition of STAT3 phosphorylation at Tyr705 residue in human MDA-MB-231 cells by sandwich-ELISA | Homo sapiens | 7 | ALA4396906 | cell-based format | Scientific Literature | |
| 6. | ALA4398940 | B | Inhibition of IL-6-induced STAT3 phosphorylation at Tyr705 residue in human MDA-MB-231 cells incubated for 12 hrs followed by IL-16 stimulation after 45 mins by Westernblot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 7. | ALA4398941 | B | Inhibition of JAK2 in human MDA-MB-231 cells assessed as decrease in JAK2 phosphorylation at 1 to 10 uM preincubated for 12 hrs followed by IL-16 stimulation after 45 mins by Westernblot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 8. | ALA4398942 | A | Effect on total JAK2 level in human MDA-MB-231 cells at 1 to 10 uM preincubated for 12 hrs followed by IL-16 stimulation after 45 mins by Western blot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 9. | ALA4398943 | B | Inhibition of EGFR in human MDA-MB-231 cells assessed as decrease in EGF-induced ERK phosphorylation at 1 to 10 uM preincubated for 12 hrs followed by EGF-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 10. | ALA4398944 | B | Inhibition of EGFR in human MDA-MB-231 cells assessed as decrease in EGF-induced EGFR phosphorylation at 1 to 10 uM preincubated for 12 hrs followed by EGF-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 11. | ALA4398945 | A | Effect on total EGFR protein level in EGF-induced human MDA-MB-231 cells at 1 to 10 uM preincubated for 12 hrs followed by EGF-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 12. | ALA4398946 | A | Effect on total ERK protein level in EGF-induced human MDA-MB-231 cells at 1 to 10 uM preincubated for 12 hrs followed by EGF-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 13. | ALA4398951 | B | Inhibition of STAT1 in human MDA-MB-231 cells assessed as reduction in IL-6-induced STAT1 phosphorylation at 1 to 10 uM preincubated for 12 hrs followed by IL-16-stimulation after 45 mins by Westernblot analysis | Homo sapiens | 1 | ALA4396906 | cell-based format | Scientific Literature | |
| 14. | ALA4398952 | B | Inhibition of EGFR (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 15. | ALA4398953 | B | Inhibition of EGFR L858R mutant (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 16. | ALA4398954 | B | Inhibition of EGFR 746-750 deletion mutant (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 17. | ALA4398955 | B | Inhibition of FGFR1 (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 18. | ALA4398956 | B | Inhibition of FGFR2 (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 19. | ALA4398957 | B | Inhibition of FGFR3 (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature | |
| 20. | ALA4398958 | B | Inhibition of FGFR4 (unknown origin) at 10 uM using peptide as substrate incubated for 10 mins by caliper assay relative to control | Homo sapiens | 1 | ALA4396906 | single protein format | Scientific Literature |
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