# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4392120 | Functional | Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation measured after 15 mins by Glosensor-based FLIPR assay | Homo sapiens | 44 | ALA4390674 | cell-based format | Scientific Literature | |
2. | ALA4392121 | Functional | Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation measured after 15 mins by Glosensor-based FLIPR assay relative to dopamine | Homo sapiens | 44 | ALA4390674 | cell-based format | Scientific Literature | |
3. | ALA4392122 | Binding | Agonist activity at recombinant C-terminal RLuc8-fused human D1 receptor expressed in HEK29T cells co-expressing N-terminal Venus-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment measured after 15 mins in presence of coelenterazine H by BRET assay | Homo sapiens | 21 | ALA4390674 | cell-based format | Scientific Literature | |
4. | ALA4392123 | Binding | Agonist activity at recombinant C-terminal RLuc8-fused human D1 receptor expressed in HEK29T cells co-expressing N-terminal Venus-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment measured after 15 mins in presence of coelenterazine H by BRET assay relative to dopamine | Homo sapiens | 21 | ALA4390674 | cell-based format | Scientific Literature |