# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4372546 | Binding | Agonist activity at Hsp70 in HEK293 cells expressing CFTR F508del mutant (unknown origin) assessed as increase in steady-state levels of CFTR mutant at 30 uM after 24 hrs by immunoblot assay | Homo sapiens | 13 | ALA4371050 | cell-based format | Scientific Literature | |
2. | ALA4372550 | Binding | Agonist activity at Hsp70 in HEK293 cells expressing CFTR F508del mutant (unknown origin) assessed as increase in steady-state levels of CFTR mutant at 100 uM after 24 hrs by immunoblot assay | Homo sapiens | 12 | ALA4371050 | cell-based format | Scientific Literature | |
3. | ALA4372551 | ADME | Cytotoxicity against HEK293H cells after 24 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371050 | cell-based format | Scientific Literature | |
4. | ALA4372552 | ADME | Cytotoxicity against HEK293H cells assessed as cell viability at 100 uM after 24 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371050 | cell-based format | Scientific Literature | |
5. | ALA4372553 | ADME | Cytotoxicity against human MCF7 cells after 24 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371050 | cell-based format | Scientific Literature | |
6. | ALA4372554 | ADME | Cytotoxicity against human MCF7 cells assessed as cell viability at 100 uM after 24 hrs by CellTiter-Glo assay | Homo sapiens | 14 | ALA4371050 | cell-based format | Scientific Literature | |
7. | ALA4372564 | ADME | Cytotoxicity against human H4 cells expressing wild type alpha-synuclein (unknown origin) assessed as reduction in cell viability after 24 hrs by CellTiter-Glo assay | Homo sapiens | 13 | ALA4371050 | cell-based format | Scientific Literature |