# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4415100 | P | Solubility of the compound in PBS with 0.05% Tween 20 and 1% DMSO | 1 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA4415101 | B | Binding affinity to CD47 in biotinylated human MEC1 cell membranes by biolayer interferometry | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
3. | ALA4415102 | F | Cytotoxicity against human MEC1 cells assessed as induction of cell death at 200 uM after 6 hrs by annexin V/propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
4. | ALA4415103 | P | Aggregation property of the compound in water | 2 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4415104 | A | Aggregation property of the compound in human serum | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
6. | ALA4415105 | F | Cytotoxicity against human MEC1 cells assessed as induction of cell death after 2 hrs by annexin V/propidium iodide staining based flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4415106 | P | Aggregation property of the compound in phosphate buffer | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA4415108 | B | Agonist activity at CD47 in human MEC1 cells assessed as activation of PLCgamma1-induced calcium-mediated caspase-independent cell death at 200 uM after 2 hrs by microscopic method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4415110 | F | Induction of cell aggregation in human MEC1 at 200 uM after 2 hrs by microcopic method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA4415111 | F | Induction of cell death in human MEC1 cells at 50 uM in presence of extracellular calcium chelator BAPTA administered 30 mins post BAPTA treatment in serum-free medium by Annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA4415112 | F | Induction of cell death in human MEC1 cells at 50 uM in presence of PLCgamma1 inhibitor U73122 administered 1 hr post U73122 treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA4415113 | F | Induction of cell death in human MEC1 cells at 50 uM in presence of IP3R inhibitor 2-APB administered 1 hr post 2-APB treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA4415114 | F | Induction of cell death in human MEC1 cells at 50 uM in presence of ryanodine inhibitor dantrolene administered 1 hr post dantrolene treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA4415118 | F | Cytotoxicity against human A549 cells assessed as induction of cell death after 6 hrs by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
15. | ALA4415119 | F | Induction of cell death in human A549 cells at 100 uM in presence of PLCgamma1 inhibitor U73122 administered 1 hr post U73122 treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA4415120 | F | Induction of cell death in human A549 cells at 100 uM in presence of IP3R inhibitor 2-APB administered 1 hr post 2-APB treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA4415121 | F | Induction of cell death in human A549 cells at 100 uM in presence of extracellular calcium chelator BAPTA administered 30 mins post BAPTA treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA4415122 | F | Induction of cell death in human A549 cells at 100 uM in presence of ryanodine inhibitor dantrolene administered 1 hr post dantrolene treatment in serum-free medium by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA4415123 | F | Induction of cell death in human A549 cells at 100 uM in presence of ryanodine inhibitor dantrolene/PLCgamma1 inhibitor U73122/IP3R inhibitor 2-APB by annexin V-APC/propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA4415128 | F | Induction of cell death in human A549 cells at 100 uM administered 30 mins post Q-VD-OPh treatment in serum-free medium by propidium iodide staining based flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |