# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4414121 | Binding | Inhibition of human 6His-tagged SHP2 (1 to 525 residues) expressed in Escherichia coli BL21 Star (DE3) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 16 | ALA4411333 | assay format | Scientific Literature | |
2. | ALA4414122 | Binding | Inhibition of of SHP2 in human KYSE520 cells assessed as suppression of ERK phosphorylation after 2 hrs by AlphaScreen SureFire Phospho-ERK1/2 assay | Homo sapiens | 15 | ALA4411333 | cell-based format | Scientific Literature | |
3. | ALA4414124 | Binding | Inhibition of human ERG by Q-patch assay | Homo sapiens | 15 | ALA4411333 | single protein format | Scientific Literature |