# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4385876 | Binding | Displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintillation counting method | Rattus norvegicus | 16 | ALA4385600 | cell-based format | Scientific Literature | |
2. | ALA4385878 | Binding | Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintillation counting method | Rattus norvegicus | 16 | ALA4385600 | cell-based format | Scientific Literature | |
3. | ALA4385882 | Binding | Displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes incubated for 1 hr in shaker by liquid scintillation counting method | Homo sapiens | 16 | ALA4385600 | cell-based format | Scientific Literature | |
4. | ALA4385887 | Binding | Selectivity ratio of Ki for displacement of [3H]-diprenorphine from rat delta-type opioid receptor expressed in rat C6 cell membranes to Ki for displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes | Rattus norvegicus | 17 | ALA4385600 | cell-based format | Scientific Literature | |
5. | ALA4385888 | Binding | Selectivity ratio of Ki for displacement of [3H]-diprenorphine from human kappa-type opioid receptor expressed in CHO cell membranes to Ki for displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes | 17 | ALA4385600 | cell-based format | Scientific Literature | ||
6. | ALA4385889 | Functional | Agonist activity at rat Mu-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by liquid scintillation counting method | Rattus norvegicus | 17 | ALA4385600 | cell-based format | Scientific Literature | |
7. | ALA4385890 | Functional | Agonist activity at rat Mu-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding at 10 uM incubated for 1 hr by liquid scintillation counting method relative to DAMGO | Rattus norvegicus | 17 | ALA4385600 | cell-based format | Scientific Literature | |
8. | ALA4385891 | ADME | Agonist activity at rat Delta-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by liquid scintillation counting method | Rattus norvegicus | 16 | ALA4385600 | cell-based format | Scientific Literature | |
9. | ALA4385892 | ADME | Agonist activity at rat Delta-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding at 10 uM incubated for 1 hr by liquid scintillation counting method relative to DPDPE | Rattus norvegicus | 16 | ALA4385600 | cell-based format | Scientific Literature | |
10. | ALA4385893 | Functional | Agonist activity at human kappa-type opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr by liquid scintillation counting method | Homo sapiens | 17 | ALA4385600 | cell-based format | Scientific Literature | |
11. | ALA4385894 | Functional | Agonist activity at human kappa-type opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding at 10 uM incubated for 1 hr by liquid scintillation counting method relative to U69593 | Homo sapiens | 17 | ALA4385600 | cell-based format | Scientific Literature | |
12. | ALA4385895 | ADME | Half life in mouse liver microsomes at 1 uM in presence of NADP by LC/MS-MS analysis | Mus musculus | 17 | ALA4385600 | microsome format | Scientific Literature | |
13. | ALA4385896 | ADME | Ratio of test compound half life to verapamil half life in mouse liver microsomes at 1 uM in presence of NADP by LC/MS-MS analysis | Mus musculus | 16 | ALA4385600 | microsome format | Scientific Literature |