# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4401445 | Functional | Antifungal activity against Cryptococcus neoformans H99 after 48 hrs by growth curve assay | Cryptococcus neoformans | 61 | ALA4400538 | organism-based format | Scientific Literature | |
2. | ALA4401446 | Functional | Antifungal activity against Candida glabrata 8535 after 48 hrs by spectrophotometery | Nakaseomyces glabratus | 3 | ALA4400538 | organism-based format | Scientific Literature | |
3. | ALA4401447 | Functional | Antifungal activity against Cryptococcus neoformans H99 after 72 hrs by growth curve assay | Cryptococcus neoformans | 3 | ALA4400538 | organism-based format | Scientific Literature | |
4. | ALA4401448 | Functional | Antifungal activity against Candida albicans 7781 after 48 hrs by spectrophotometery | Candida albicans | 3 | ALA4400538 | organism-based format | Scientific Literature | |
5. | ALA4401449 | Functional | Antifungal activity against Candida albicans 0304103 after 48 hrs by spectrophotometery | Candida albicans | 3 | ALA4400538 | organism-based format | Scientific Literature | |
6. | ALA4401450 | Functional | Antifungal activity against Candida parapsilosis 5008 after 48 hrs by spectrophotometery | Candida parapsilosis | 3 | ALA4400538 | organism-based format | Scientific Literature | |
7. | ALA4401451 | Functional | Antifungal activity against Aspergillus fumigatus 7544 after 48 hrs by spectrophotometery | Aspergillus fumigatus | 3 | ALA4400538 | organism-based format | Scientific Literature | |
8. | ALA4401452 | Functional | Antifungal activity against Trichophyton rubrum TIA after 48 hrs by spectrophotometery | Trichophyton rubrum | 3 | ALA4400538 | organism-based format | Scientific Literature | |
9. | ALA4401453 | Functional | Antifungal activity against Microsporum gypseum MZC after 48 hrs by spectrophotometery | Nannizzia gypsea | 3 | ALA4400538 | organism-based format | Scientific Literature | |
10. | ALA4401454 | Functional | Antifungal activity against Cryptococcus neoformans ATCC 34877 after 72 hrs by spectrophotometery | Cryptococcus neoformans | 3 | ALA4400538 | organism-based format | Scientific Literature | |
11. | ALA4401455 | Functional | Antifungal activity against Cryptococcus gattii ATCC 14116 after 72 hrs by spectrophotometery | Cryptococcus gattii | 3 | ALA4400538 | organism-based format | Scientific Literature | |
12. | ALA4401456 | ADME | Protein binding in mouse plasma | Mus musculus | 2 | ALA4400538 | cell-free format | Scientific Literature | |
13. | ALA4401457 | ADME | Cytotoxicity against human HUVEC | Homo sapiens | 2 | ALA4400538 | cell-based format | Scientific Literature | |
14. | ALA4401458 | Functional | Antibiofilm activity against Cryptococcus neoformans H99 at 16 ug/ml after 90 mins by XTT assay | Cryptococcus neoformans | 2 | ALA4400538 | organism-based format | Scientific Literature | |
15. | ALA4401461 | Functional | Inhibition of melanin production in Cryptococcus neoformans H99 at 2.5 ug/ml | Cryptococcus neoformans | 3 | ALA4400538 | organism-based format | Scientific Literature | |
16. | ALA4401462 | Functional | Inhibition of urease production in Cryptococcus neoformans H99 at 10 ug/ml | Cryptococcus neoformans | 2 | ALA4400538 | organism-based format | Scientific Literature | |
17. | ALA4401463 | ADME | Half life in ICR mouse liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 3 | ALA4400538 | microsome format | Scientific Literature | |
18. | ALA4401464 | ADME | Clearance in ICR mouse liver microsomes at 1 uM measured up to 45 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 3 | ALA4400538 | microsome format | Scientific Literature | |
19. | ALA4401485 | Physicochemical | Solubility of the compound | 3 | ALA4400538 | small-molecule physicochemical format | Scientific Literature | ||
20. | ALA4401486 | Functional | Antifungal activity against Cryptococcus neoformans H99 assessed as inhibition of microbial growth at 8 ug/ml after 12 to 48 hrs by growth curve assay | Cryptococcus neoformans | 2 | ALA4400538 | organism-based format | Scientific Literature |