#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4402926	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasite-free adipose tissue in acute phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 8 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection measured after day 100 post infection by PCR method relative to control	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
2.	ALA4402927	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasite-free adipose tissue in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection measured after day 100 post infection by PCR method relative to control	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
3.	ALA4402930	Toxicity	Toxicity in BALB/c mouse infected with Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigotes assessed as decrease in serum alkaline phosphatase level in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection measured on day 100 post infection relative to control	Mus musculus	2	ALA4402517	organism-based format	Scientific Literature
4.	ALA4402932	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasitemia reactivation in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection by Neubauer chamber relative to control	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
5.	ALA4402933	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote infected in BALB/c mouse assessed as parasitemia reactivation in acute phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 8 post infection followed by cyclophosphamide induced immunosuppression on day 80 post infection by Neubauer chamber relative to control	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
6.	ALA4402934	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigotes infected in BALB/c mouse assessed as reduction in serum Ig-G level in acute phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 8 post infection and measured at day 14 post infection by ELISA	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
7.	ALA4402936	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 epimastigote assessed as effect on parasite glycolytic pathway by measuring decrease in succinate excretion at IC50 after 72 hrs by H NMR method relative to control	Trypanosoma cruzi	1	ALA4402517	organism-based format	Scientific Literature
8.	ALA4402937	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigotes infected in BALB/c mouse assessed as reduction in serum Ig-G level in chronic phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 70 post infection measured at day 76 post infection by ELISA	Trypanosoma cruzi	3	ALA4402517	organism-based format	Scientific Literature
9.	ALA4402938	Toxicity	Toxicity in BALB/c mouse infected with Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 bloodstream trypomastigote assessed as decrease in serum uric acid level in acute phase at 20 mg/kg/day, po administered for 5 consecutive days starting from day 8 post infection and measured on day 100 post infection by biochemical analysis relative to control	Mus musculus	2	ALA4402517	organism-based format	Scientific Literature
10.	ALA4402939	Toxicity	Genotoxicity in Salmonella typhimurium TA1535 harboring pSK1002 assessed as survival at 0.5 mg/ml in absence of Sprague-Dawley rat liver S9 fraction metabolic activation by SOS/umu assay relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	2	ALA4402517	assay format	Scientific Literature
11.	ALA4402940	Toxicity	Genotoxicity in Salmonella typhimurium TA1535 harboring pSK1002 assessed as umu gene induction at 0.008 mg/ml in presence of Sprague-Dawley rat liver S9 fraction metabolic activation by SOS/umu assay relative to control	Salmonella enterica subsp. enterica serovar Typhimurium	2	ALA4402517	subcellular format	Scientific Literature
12.	ALA4402941	ADME	Cytotoxicity against African green monkey Vero cells measured after 72 hrs by MTT assay	Chlorocebus sabaeus	11	ALA4402517	cell-based format	Scientific Literature
13.	ALA4402942	Functional	Antitrypanosomal activity against Trypanosoma cruzi TINF/CH/1956/Tulahuen;DTU 6 epimastigotes measured after 72 hrs by Neubauer hemocytometer	Trypanosoma cruzi	11	ALA4402517	organism-based format	Scientific Literature
14.	ALA4402943	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 epimastigotes measured after 72 hrs by Neubauer hemocytometer	Trypanosoma cruzi	11	ALA4402517	organism-based format	Scientific Literature
15.	ALA4402944	Functional	Antitrypanosomal activity against Trypanosoma cruzi IRHOD/CO/2008/SN3;DTU 1 epimastigotes measured after 72 hrs by Neubauer hemocytometer	Trypanosoma cruzi	11	ALA4402517	organism-based format	Scientific Literature
16.	ALA4402945	Toxicity	Selectivity index, ratio of IC50 for African green monkey Vero cells to IC50 for Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5		11	ALA4402517	assay format	Scientific Literature
17.	ALA4402946	Toxicity	Selectivity index, ratio of IC50 for African green monkey Vero cells to IC50 for Trypanosoma cruzi IRHOD/CO/2008/SN3;DTU 1		11	ALA4402517	assay format	Scientific Literature
18.	ALA4402947	Toxicity	Selectivity index, ratio of IC50 for African green monkey Vero cells to IC50 for Trypanosoma cruzi TINF/CH/1956/Tulahuen;DTU 6		11	ALA4402517	assay format	Scientific Literature
19.	ALA4402948	Functional	Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa;DTU 5 amastigote forms measured after 72 hrs by Giemsa staining based assay	Trypanosoma cruzi	6	ALA4402517	organism-based format	Scientific Literature
20.	ALA4402949	Functional	Antitrypanosomal activity against bloodstream trypomastigote stage of Trypanosoma cruzi MHOM/Pe/2011/Arequipa; DTU 5 isolated from parasite infected BALB/c Albino mouse cardiac cells after 24 hrs by Neubauer chamber based cell counting method	Trypanosoma cruzi	6	ALA4402517	organism-based format	Scientific Literature