# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4410458 | Functional | Antifungal activity against Cryptococcus neoformans incubated for 72 hrs by broth micro dilution method | Cryptococcus neoformans | 32 | ALA4406888 | organism-based format | Scientific Literature | |
2. | ALA4410459 | Functional | Antifungal activity against Cryptococcus gattii incubated for 72 hrs by broth micro dilution method | Cryptococcus gattii | 32 | ALA4406888 | assay format | Scientific Literature | |
3. | ALA4410460 | ADME | Half life in human liver microsomes at 1 uM preincubated for 5 mins followed by NADPH addition and measured for 45 mins by LC/MS analysis | Homo sapiens | 13 | ALA4406888 | microsome format | Scientific Literature | |
4. | ALA4410461 | ADME | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 3 uM by CellTiter-Glo luminescent cell viability assay relative to control | Homo sapiens | 6 | ALA4406888 | cell-based format | Scientific Literature | |
5. | ALA4410462 | Binding | Antifungal activity against Candida albicans GWT1 expressed in Saccharomyces cerevisiae assessed as overexpression ratio | Candida albicans | 5 | ALA4406888 | assay format | Scientific Literature | |
6. | ALA4410463 | ADME | Inhibition of human PIGW expressed in Saccharomyces cerevisiae at 16 uM by spectrophotometric analysis relative to control | Homo sapiens | 5 | ALA4406888 | assay format | Scientific Literature |