| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4325476 | Functional | Neuroprotective activity against oxygen-glucose deprivation-induced toxicity in human SH-SY5Y cells assessed as cell viability at 1 uM preincubated for 2 hrs followed by OGD-challenge and measured after 24 hrs by MTT assay (Rvb = 54.92 +/- 2.12%) | Homo sapiens | 30 | ALA4321877 | cell-based format | Scientific Literature | |
| 2. | ALA4325477 | Functional | Neuroprotective activity against oxygen-glucose deprivation-induced toxicity in human SH-SY5Y cells assessed as cell viability at 10 uM preincubated for 2 hrs followed by OGD-challenge and measured after 24 hrs by MTT assay (Rvb = 54.92 +/- 2.12%) | Homo sapiens | 30 | ALA4321877 | cell-based format | Scientific Literature | |
| 3. | ALA4325484 | Functional | Neuroprotective activity against oxygen-glucose deprivation-induced toxicity in human SH-SY5Y cells assessed as cell viability at 2 uM preincubated for 2 hrs followed by OGD-challenge and measured after 24 hrs by MTT assay (Rvb = 54.92 +/- 2.12%) | Homo sapiens | 3 | ALA4321877 | cell-based format | Scientific Literature | |
| 4. | ALA4325486 | Functional | Antioxidant activity assessed as trolox equivalent of AAPH radical scavenging activity measured every min for 180 mins by ORAC-FL assay | 8 | ALA4321877 | assay format | Scientific Literature | ||
| 5. | ALA4325487 | ADME | Permeability of the compound incubated for 10 hrs by PAMPA | 8 | ALA4321877 | assay format | Scientific Literature |
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