# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4386804 | Functional | Positive allosteric modulation of human M4 AchR expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization | Homo sapiens | 40 | ALA4385625 | cell-based format | Scientific Literature | |
2. | ALA4386805 | Functional | Positive allosteric modulation of human M4 AchR expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization relative to acetylcholine alone | Homo sapiens | 40 | ALA4385625 | cell-based format | Scientific Literature | |
3. | ALA4386815 | ADME | Fraction unbound in rat brain | Rattus norvegicus | 2 | ALA4385625 | tissue-based format | Scientific Literature | |
4. | ALA4386816 | ADME | Efflux ratio of permeability in dog MDCK-MDR1 cells | Canis lupus familiaris | 14 | ALA4385625 | cell-based format | Scientific Literature |