#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4362422	Binding	Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as increase in blue shift in maximum absorption at 0.2 uM by fluorescence based assay	Homo sapiens	3	ALA4359875	single protein format	Scientific Literature
2.	ALA4362424	Binding	Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assay	Homo sapiens	4	ALA4359875	single protein format	Scientific Literature
3.	ALA4362425	Physicochemical	Photostability of compound		4	ALA4359875	small-molecule physicochemical format	Scientific Literature
4.	ALA4362426	ADME	Stability in mouse plasma assessed as remaining compound at 50 uM incubated for 30 to 60 mins by HPLC analysis	Mus musculus	4	ALA4359875	cell-free format	Scientific Literature
5.	ALA4362427	Toxicity	Dark toxicity against human SH-SY5Y cells assessed as reduction in cell viability at 50 uM incubated for 24 hrs by MTT assay	Homo sapiens	4	ALA4359875	cell-based format	Scientific Literature
6.	ALA4362428	Binding	Binding affinity to amyloid beta 1 to 42 in double transgenic C57BL/6 APPswe/PSEN1 mouse assessed as plaque formation in cortex region at 1 uM incubated for 5 mins by fluorescence microscopy	Mus musculus	1	ALA4359875	assay format	Scientific Literature
7.	ALA4362429	Binding	Binding affinity to amyloid beta 1 to 42 in C57BL/6 mouse brain cortex assessed as plague formation at 1 uM incubated for 5 mins by fluorescence microscopy	Mus musculus	1	ALA4359875	assay format	Scientific Literature
8.	ALA4362430	Functional	In vivo binding affinity to amyloid beta 1 to 42 in APP/PS1 double transgenic C57BL/6 mouse brain assessed as amyloid-beta plaque-compound complex formation at 4 mg/kg, iv measured for 5 to 60 mins by NIR imaging analysis	Mus musculus	1	ALA4359875	organism-based format	Scientific Literature
9.	ALA4362431	Functional	In vivo binding affinity to amyloid beta 1 to 42 in C57BL/6 mouse brain assessed as amyloid-beta plaque-compound complex formation at 4 mg/kg, iv measured for 5 to 60 mins by NIR imaging analysis	Mus musculus	1	ALA4359875	organism-based format	Scientific Literature
10.	ALA4362432	Binding	Inhibition of amyloid beta 1 to 42 aggregation in human SH-SY5Y cells incubated for 48 hrs by fluorescence microscopy	Homo sapiens	1	ALA4359875	cell-based format	Scientific Literature
11.	ALA4362435	Binding	Binding affinity to amyloid beta 1 to 42 in double transgenic C57BL/6 APPswe/PSEN1 mouse assessed as plaque formation in hippocampus region at 1 uM incubated for 5 mins by fluorescence microscopy	Mus musculus	1	ALA4359875	single protein format	Scientific Literature
12.	ALA4362436	Binding	Binding affinity to amyloid beta 1 to 42 in C57BL/6 mouse brain hippocampus assessed as plague formation at 1 uM incubated for 5 mins by fluorescence microscopy	Mus musculus	1	ALA4359875	assay format	Scientific Literature