# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4401323 | Binding | Inhibition of HIV1 reverse transcriptase RNase H expressed in Escherichia coli JM109 using RNA/DNA duplex substrate HTS-1 | Human immunodeficiency virus 1 | 24 | ALA4400534 | assay format | Scientific Literature | |
2. | ALA4401324 | Binding | Inhibition of HIV1 reverse transcriptase polymerase using deoxynucleotide triphosphates and 18 nucleotide DNA primer annealed to 100 nucleotide DNA template after 30 mins | Human immunodeficiency virus 1 | 24 | ALA4400534 | single protein format | Scientific Literature | |
3. | ALA4401325 | Binding | Inhibition of HIV1 integrase strand transfer activity using 5'-biotinylated oligonucleotide as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins | Human immunodeficiency virus 1 | 24 | ALA4400534 | single protein format | Scientific Literature | |
4. | ALA4401326 | Functional | Antiviral activity against HIV-1 infected in human P4R5 cells assessed as reduction in viral replication preincubated for 24 hrs followed by viral infection and measured after 48 hrs by MAGI assay | Human immunodeficiency virus 1 | 23 | ALA4400534 | organism-based format | Scientific Literature | |
5. | ALA4401327 | ADME | Cytotoxicity against human P4R5 cells after 72 hrs by XTT assay | Homo sapiens | 21 | ALA4400534 | cell-based format | Scientific Literature |