# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4401742 | Binding | Inhibition of mouse GAT-1 expressed in HEK293 cells assessed as decrease in [3H]GABA uptake preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by scintillation counting analysis | Mus musculus | 10 | ALA4400545 | cell-based format | Scientific Literature | |
2. | ALA4401746 | Binding | Binding affinity to mouse GAT-1 expressed in HEK293 cells after 4 hrs in presence of NO711 by LC-ESI-MS/ms analysis | Mus musculus | 11 | ALA4400545 | cell-based format | Scientific Literature | |
3. | ALA4401747 | Binding | Inhibition of mouse GAT-2 expressed in HEK293 cells assessed as remaining [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition and measured after 10 mins by scintillation counting analysis | Mus musculus | 4 | ALA4400545 | cell-based format | Scientific Literature | |
4. | ALA4401748 | Binding | Inhibition of mouse GAT-3 expressed in HEK293 cells assessed as remaining [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by scintillation counting analysis | Mus musculus | 4 | ALA4400545 | cell-based format | Scientific Literature | |
5. | ALA4401749 | Binding | Inhibition of mouse GAT-4 expressed in HEK293 cells assessed as remaining [3H]GABA uptake at 100 uM preincubated for 25 mins followed by [3H]GABA addition and measured after 4 mins by scintillation counting analysis | Mus musculus | 4 | ALA4400545 | cell-based format | Scientific Literature |