| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4311224 | B | Inhibition of PDK1 (unknown origin) at 10 uM using PDH E1 as substrate measured after 30 mins by kinase-glo assay relative to control | Homo sapiens | 4 | ALA4308888 | single protein format | Scientific Literature | |
| 2. | ALA4311226 | B | Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assay | Homo sapiens | 5 | ALA4308888 | single protein format | Scientific Literature | |
| 3. | ALA4311227 | B | Potency index, ratio of DCA EC50 to test compound EC50 for inhibition of PDK1 (unknown origin) | Homo sapiens | 4 | ALA4308888 | single protein format | Scientific Literature | |
| 4. | ALA4311228 | B | Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysis | Homo sapiens | 5 | ALA4308888 | assay format | Scientific Literature | |
| 5. | ALA4311229 | B | Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysis | Homo sapiens | 4 | ALA4308888 | assay format | Scientific Literature | |
| 6. | ALA4311230 | B | Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysis | Homo sapiens | 4 | ALA4308888 | assay format | Scientific Literature | |
| 7. | ALA4311231 | B | Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysis | Homo sapiens | 4 | ALA4308888 | assay format | Scientific Literature | |
| 8. | ALA4311232 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level at 10 uM by ELISA | Homo sapiens | 4 | ALA4308888 | cell-based format | Scientific Literature | |
| 9. | ALA4311233 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level by ELISA | Homo sapiens | 2 | ALA4308888 | cell-based format | Scientific Literature | |
| 10. | ALA4311234 | B | Inhibition of PDK in human NCI-H1975 cells assessed as reduction in phosphorylated S293 PDC E1 level by Western blot analysis | Homo sapiens | 2 | ALA4308888 | cell-based format | Scientific Literature | |
| 11. | ALA4311236 | F | Antiproliferative activity against human NCI-H1975 cells assessed as reduction in cell viability at 10 uM after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4308888 | cell-based format | Scientific Literature | |
| 12. | ALA4311237 | A | Cytotoxicity against human MRC5 cells assessed as reduction in cell viability up to 40 uM after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4308888 | cell-based format | Scientific Literature | |
| 13. | ALA4311239 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | ALA4308888 | cell-based format | Scientific Literature | |
| 14. | ALA4311240 | F | Antiproliferative activity against human NCI-H1650 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 4 | ALA4308888 | cell-based format | Scientific Literature |
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