# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341304 | Binding | Poison activity at recombinant human TOP1 expressed in baculovirus infected Sf9 insect cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 27 | ALA4340526 | cell-based format | Scientific Literature | |
2. | ALA4341332 | Binding | Poison activity at TOP1 in human MCF7 cells assessed as decrease in relaxed supercoiled pBS(SK+) DNA mobility measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 27 | ALA4340526 | cell-based format | Scientific Literature | |
3. | ALA4772332 | Binding | Inhibition of recombinant human Top1 expressed in baculovirus infected sf9 insect cells using supercoiled pBS (SK+) DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis analysis | Homo sapiens | 11 | ALA4765384 | cell-based format | Scientific Literature | |
4. | ALA4772333 | Binding | Inhibition of Top1 in human MCF7 cells using supercoiled pBS (SK+) DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis analysis | Homo sapiens | 11 | ALA4765384 | cell-based format | Scientific Literature |