| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4395639 | Functional | Antiviral activity against wild type HIV-1 3B infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 26 | ALA4393704 | organism-based format | Scientific Literature | |
| 2. | ALA4395640 | Functional | Antiviral activity against HIV-1 3B harboring reverse transcriptase E138K mutant infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 26 | ALA4393704 | organism-based format | Scientific Literature | |
| 3. | ALA4395641 | Functional | Antiviral activity against HIV-1 3B harboring reverse transcriptase RES056 mutant infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 26 | ALA4393704 | organism-based format | Scientific Literature | |
| 4. | ALA4395642 | ADME | Cytotoxicity against human MT4 cells measured after 5 days by MTT assay | Homo sapiens | 26 | ALA4393704 | cell-based format | Scientific Literature | |
| 5. | ALA4395643 | Toxicity | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for HIV-1 3B infected in MT4 cells | 26 | ALA4393704 | cell-based format | Scientific Literature | ||
| 6. | ALA4395644 | Binding | Inhibition of recombinant wild-type HIV1 3B reverse transcriptase assessed as reduction in biotin-dUTP incorporation using poly(rA)/oligo(dT)16 as template primer incubated for 1 hr followed by the addition of (DIG)-dUTP and biotin-labeled dNTPs by ELISA | Human immunodeficiency virus 1 | 7 | ALA4393704 | single protein format | Scientific Literature | |
| 7. | ALA4395645 | Functional | Potency index, ratio of ETV EC50 to compound EC50 for antiviral activity against wild type HIV-1 3B infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 1 | ALA4393704 | organism-based format | Scientific Literature | |
| 8. | ALA4395646 | Functional | Potency index, ratio of EFV EC50 to compound EC50 for antiviral activity against wild type HIV-1 3B infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 1 | ALA4393704 | organism-based format | Scientific Literature | |
| 9. | ALA4395647 | Functional | Potency index, ratio of ETV EC50 to compound EC50 for antiviral activity against HIV-1 3B harboring reverse transcriptase E138K mutant infected in MT4 cells measured after 5 days by MTT assay | Human immunodeficiency virus 1 | 1 | ALA4393704 | organism-based format | Scientific Literature |
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