#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4305488	Functional	Antiproliferative activity against human SMMC7721 assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
2.	ALA4305489	Functional	Induction of cytoplasmic vacuolation in human SMMC7721 cells assessed as increase in number of vacuoles formation with shrinked volume of vacuoles at 3 to 10 uM incubated for 48 hrs by inverted phase contrast microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
3.	ALA4305490	Functional	Induction of cell morphological changes in human SMMC7721 cells assessed as cell shrinkage at 3 to 10 uM incubated for 48 hrs by HE staining based light microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
4.	ALA4305491	Functional	Induction of cell morphological changes in human SMMC7721 cells assessed as cytoplasmic loss at 3 to 10 uM incubated for 48 hrs by H and E staining based light microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
5.	ALA4305492	Functional	Induction of endoplasmic reticulum vacuolation in human SMMC7721 cells assessed as nuclei shrank and appearance of vacuoles surrounded by positive ER-specific markers at 3 to 5 uM incubated for 48 hrs by ER-tracker red and Hoechst 33342 staining based laser scanning confocal microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
6.	ALA4305493	Functional	Induction of endoplasmic reticulum vacuolation in human SMMC7721 cells assessed as increase in vacuole formation and entire ER cytoplasm occupied with vacuole with loss of cell contents at 3 to 5 uM incubated for 48 hrs by ER-tracker red and Hoechst 33342 staining based laser scanning confocal microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
7.	ALA4305494	Functional	Induction of cell morphological changes in human SMMC7721 cells assessed as appearance of large vacuoles in cytoplasm at 5 uM incubated for 48 hrs by transmission electron microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
8.	ALA4305495	Functional	Induction of endoplasmic reticulum vacuolation in human SMMC7721 cells assessed as vacuole derivatization by expansion and swelling of rough ER with vacuoles wrapped in monolayer membranes with loss of ER structure integrity at 5 uM incubated for 48 hrs by transmission electron microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
9.	ALA4305496	Functional	Induction of mitochondrial swelling, vacuoles and ridges disappearance and loss of mitochondrial and golgi apparatus structural integrity in human SMMC7721 cells at 5 uM incubated for 48 hrs by transmission electron microscopy	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
10.	ALA4305497	Functional	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
11.	ALA4305498	Functional	Antiproliferative activity against human CNE2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
12.	ALA4305500	Functional	Antiproliferative activity against human SMMC7721 cells assessed as decrease in cell viability incubated for 48 hrs by CCK-8 assay	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
13.	ALA4305501	Functional	Induction of apoptosis with PS translocation in human SMMC7721 cells at 3 to 10 uM incubated for 48 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry	Homo sapiens	2	ALA4304750	cell-based format	Scientific Literature
14.	ALA4305502	Functional	Induction of apoptosis in human SMMC7721 cells assessed as viable cells with normal cell membrane at 10 uM incubated for 48 hrs by Annexin V-FITC and propidium iodide staining based flow cytometry	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
15.	ALA4305503	Functional	Induction of cell cycle arrest in human SMMC7721 cells at 3 to 10 uM incubated for 48 hrs by propidium iodide staining based flow cytometry	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
16.	ALA4305504	Functional	Effect on cleaved caspase 3 level in human SMMC7721 cells at antiproliferative IC60 incubated for 12 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
17.	ALA4305505	Functional	Induction of endoplasmic reticulum stress in human SMMC7721 cells assessed as increase in GRP78 expression at 3 uM by Western blot analysis	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
18.	ALA4305506	Functional	Increase in LC3-II/LC3-I expression ratio in human SMMC7721 cells at 3 uM incubated for 12 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
19.	ALA4305507	Functional	Inhibition of autophagosome formation in human SMMC7721 cells assessed as increase in p62 level at 3 uM incubated for 12 to 48 hrs by Western blot analysis	Homo sapiens	1	ALA4304750	cell-based format	Scientific Literature
20.	ALA4305508	Functional	Induction of paraptosis in human SMMC7721 cells assessed as increase in GRP78 expression by Western blot analysis	Homo sapiens	3	ALA4304750	cell-based format	Scientific Literature