# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4322964 | Binding | Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | Homo sapiens | 16 | ALA4321814 | single protein format | Scientific Literature | |
2. | ALA4322966 | Binding | Inhibition of human cathepsin L assessed as Kinact /Ki ratio using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry | Homo sapiens | 16 | ALA4321814 | single protein format | Scientific Literature | |
3. | ALA4322970 | Functional | Antitrypanosomal activity against Trypanosoma cruzi amastigote stage forms infected in mouse C2C12 cells incubated for 3 days by 4',6-diamidino-2-phenylindole staining based microscopy | Trypanosoma cruzi | 17 | ALA4321814 | organism-based format | Scientific Literature | |
4. | ALA4322971 | Binding | Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence based assay | Trypanosoma cruzi | 16 | ALA4321814 | assay format | Scientific Literature | |
5. | ALA4322972 | ADME | Cytotoxicity in mouse C2C12 cells assessed as reduction in cell viability incubated for 3 days | Mus musculus | 16 | ALA4321814 | cell-based format | Scientific Literature |