# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4366085 | Binding | Inhibition of human recombinant CETP assessed as reduction in [3H]CE/HDL transfer incubated for 4 hrs by scintillation proximity assay | Homo sapiens | 15 | ALA4364272 | single protein format | Scientific Literature | |
2. | ALA4366086 | Binding | Inhibition of CETP in human whole plasma assessed as reduction in [3H]-CE/HDL transfer incubated for 2.5 hrs by topcount scintillation counting assay | Homo sapiens | 15 | ALA4364272 | cell-free format | Scientific Literature | |
3. | ALA4366087 | ADME | Stability in human liver microsomes assessed as parent compound remaining at 50 uM preincubated for 5 to 7 mins followed by NADPH addition and measured 10 mins post-dose by LC-MS/MS | Homo sapiens | 14 | ALA4364272 | microsome format | Scientific Literature | |
4. | ALA4366088 | ADME | Stability in mouse liver microsomes assessed as parent compound remaining at 50 uM preincubated for 5 to 7 mins followed by NADPH addition and measured 10 mins post-dose by LC-MS/MS | Mus musculus | 14 | ALA4364272 | microsome format | Scientific Literature | |
5. | ALA4366089 | Binding | Inhibition of human ERG expressed in HEK293 cells by whole cell patch clamp method | Homo sapiens | 14 | ALA4364272 | cell-based format | Scientific Literature |