#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4345875	Binding	Inverse agonist activity at recombinant human GAL4-fused RORgammat LBD (247 to 497 residues) transfected in HEK293T cells assessed as inhibition of RORgammat driven transcriptional activity incubated for 24 hrs by dual-luciferase reporter gene assay	Homo sapiens	14	ALA4342512	cell-based format	Scientific Literature
2.	ALA4345876	ADME	Metabolic stability in human liver microsomes assessed as intrinsic clearance	Homo sapiens	12	ALA4342512	microsome format	Scientific Literature
3.	ALA4345877	ADME	Metabolic stability in mouse liver microsomes assessed as intrinsic clearance	Mus musculus	4	ALA4342512	microsome format	Scientific Literature
4.	ALA4345878	ADME	Protein binding in human plasma	Homo sapiens	4	ALA4342512	cell-free format	Scientific Literature
5.	ALA4345879	ADME	Protein binding in mouse plasma	Mus musculus	4	ALA4342512	cell-free format	Scientific Literature
6.	ALA4345880	Physicochemical	Solubility of compound in aqueous medium at pH 6.8		4	ALA4342512	small-molecule physicochemical format	Scientific Literature
7.	ALA4345881	ADME	Apparent permeability across apical to basolateral side in human Caco2 cells	Homo sapiens	4	ALA4342512	cell-based format	Scientific Literature
8.	ALA4345882	ADME	Apparent permeability across basolateral to apical side in human Caco2 cells	Homo sapiens	4	ALA4342512	cell-based format	Scientific Literature
9.	ALA4345883	ADME	Bioavailability in mouse at 2 umol/kg, po and 1 umol/kg, iv administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
10.	ALA4345884	ADME	AUC in mouse at 2 umol/kg, po administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
11.	ALA4345885	ADME	Clearance in mouse at 2 umol/kg, po and 1 umol/kg, iv administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
12.	ALA4345886	ADME	Unbound clearance in mouse at 2 umol/kg, po and 1 umol/kg, iv administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
13.	ALA4345887	ADME	Volume of distribution at steady state in mouse at 2 umol/kg, po and 1 umol/kg, iv administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
14.	ALA4345888	ADME	Half life in mouse at 2 umol/kg, po administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
15.	ALA4345889	ADME	Half life in mouse at 1 umol/kg, iv administered using cassette dosing	Mus musculus	4	ALA4342512	organism-based format	Scientific Literature
16.	ALA4345890	Functional	In vivo inhibition of IL18/IL23-induced IL-17A level in C57BL/6 mouse plasma administered orally once 3 hrs prior to IL-18/IL-23 stimulation and measured after 4 hrs by mesoscale assay kit method	Mus musculus	1	ALA4342512	organism-based format	Scientific Literature
17.	ALA4345894	Binding	Inhibition of RORgammat in human whole blood assessed as reduction in anti-CD3/anti-CD28 monoclonal antibodies/IL-18/IL-23-stimulated IL-17A production incubated for 2 days by mesoscale assay kit method	Homo sapiens	1	ALA4342512	tissue-based format	Scientific Literature