#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4394735	A	Clearance in C57BL/6 mouse at 1 mg/kg, iv or 10 mg/kg, po administered via gavage by HPLC-MS/MS analysis	Mus musculus	5		organism-based format	Scientific Literature
2.	ALA4394736	B	Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-5-sulfo-3H-indol-1-ium binding to biotin-labeled recombinant human FD expressed in Escherichia coli measured after 2 hrs by TR-FRET assay	Homo sapiens	17		assay format	Scientific Literature
3.	ALA4394737	P	Solubility of the compound at pH 6.8		1		small-molecule physicochemical format	Scientific Literature
4.	ALA4394738	A	Oral bioavailability in C57BL/6 mouse 10 mg/kg by HPLC-MS/MS analysis	Mus musculus	5		organism-based format	Scientific Literature
5.	ALA4394739	B	Selectivity ratio of IC50 for tryptase-beta2 (unknown origin) to IC50 for inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-5-sulfo-3H-indol-1-ium binding to biotin-labeled recombinant human FD expressed in Escherichia coli	Homo sapiens	6		assay format	Scientific Literature
6.	ALA4394740	B	Selectivity ratio of IC50 for F11a (unknown origin) to IC50 for inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-5-sulfo-3H-indol-1-ium binding to biotin-labeled recombinant human FD expressed in Escherichia coli	Homo sapiens	6		assay format	Scientific Literature
7.	ALA4394741	B	Inhibition of FD-mediated alternative complementation pathway in 50% human whole blood assessed as reduction in zymosan-induced membrane-attack complex formation preincubated for 15 mins followed by zymosan stimulation and measured after 40 mins by ELISA	Homo sapiens	17		tissue-based format	Scientific Literature
8.	ALA4394742	A	Apparent permeability of the compound by PAMPA		17		assay format	Scientific Literature
9.	ALA4394743	B	Inhibition of F11a (unknown origin)	Homo sapiens	10		single protein format	Scientific Literature
10.	ALA4394744	B	Inhibition of tryptase-beta2 (unknown origin)	Homo sapiens	10		single protein format	Scientific Literature
11.	ALA4621379	B	Inhibition of human F11a using D-Leu-Pro-Arg*Rh110-D-Pro as substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by fluorescence assay	Homo sapiens	23		single protein format	Scientific Literature
12.	ALA4621383	A	Inhibition of human complement FD by TR-FRET assay	Homo sapiens	22		single protein format	Scientific Literature
13.	ALA4729958	F	Antagonist activity at human SUCNR1 expressed in human CHEM1 cells incubated for 60 mins in presence of [35S]GTPgammaS by scintillation proximity assay	Homo sapiens	19		cell-based format	Scientific Literature
14.	ALA4729961	A	Permeability of compound by PAMPA assay		19		assay format	Scientific Literature
15.	ALA4729962	B	Inhibition of recombinant human CFD expressed in Escherichia coli incubated up to 2 hrs by TR-FRET assay	Homo sapiens	3		assay format	Scientific Literature
16.	ALA4729963	B	Inhibition of human factor 11a by TR-FRET assay	Homo sapiens	3		single protein format	Scientific Literature
17.	ALA4729964	P	Ionization constant (acid), pKa of the compound by UV metric assay		4		small-molecule physicochemical format	Scientific Literature
18.	ALA4729966	A	Oral bioavailability in C57BL/6 mouse at 10 mg/kg measured after 0.25 to 24 hrs by LC-MS/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
19.	ALA4729968	A	Dose normalized AUC in C57BL/6 mouse at 10 mg/kg, po measured after 0.25 to 24 hrs by LC-MS/MS analysis	Mus musculus	2		organism-based format	Scientific Literature
20.	ALA4729969	A	Clearance in C57BL/6 mouse at 1 mg/kg, iv administered as bolus dose measured after 0.083 to 24 hrs by LC-MS/MS analysis	Mus musculus	8		organism-based format	Scientific Literature