# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4409130 | Functional | Induction of singlet oxygen generation in DMSO solution assessed as singlet oxygen quantum yield by measuring reduction in DPBF irradiated with 650 nanometer laser light | 3 | ALA4406848 | assay format | Scientific Literature | ||
2. | ALA4409131 | Functional | Induction of singlet oxygen generation in TBS solution assessed as singlet oxygen quantum yield by measuring reduction in ADMA irradiated with 650 nanometer laser light | 3 | ALA4406848 | assay format | Scientific Literature | ||
3. | ALA4409132 | Unassigned | Photostability of compound in TBS assessed as percentage of photodegradation measured every 10 mins for 1 hr at 17.5 mW/cm'2 irradiation by UV-visible spectrophotometry | 2 | ALA4406848 | assay format | Scientific Literature | ||
4. | ALA4409133 | Binding | Binding affinity to calf thymus DNA assessed as percentage of hypochromicity incubated for 10 mins by UV-visible spectrophotometry | Bos taurus | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
5. | ALA4409134 | Binding | Binding affinity to calf thymus DNA assessed as binding constant incubated for 10 mins by UV-visible spectrophotometry | Bos taurus | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
6. | ALA4409135 | Binding | Competitive binding affinity to calf thymus DNA assessed as change in viscosity incubated for 10 mins by viscometer | Bos taurus | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
7. | ALA4409136 | Binding | Competitive binding affinity to calf thymus DNA assessed as binding constant in presence of ethidium bromide incubated for 10 mins by UV-visible spectrophotometry | Bos taurus | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
8. | ALA4409137 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage at 3.125 to 25 uM incubated for 1 hr in dark by agarose gel electrophoresis | Escherichia coli | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
9. | ALA4409139 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage assessed as decrease in supercoiled DNA at 3.125 uM in presence of light irradiation and incubated for 1 hr by agarose gel electrophoresis relative to control | Escherichia coli | 2 | ALA4406848 | nucleic acid format | Scientific Literature | |
10. | ALA4409142 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage assessed as increase in nicked circular DNA at 50 uM in presence of light irradiation and incubated for 1 hr by agarose gel electrophoresis | Escherichia coli | 1 | ALA4406848 | nucleic acid format | Scientific Literature | |
11. | ALA4409143 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage assessed as decrease in supercoiled DNA at 50 uM in presence of light irradiation and incubated for 1 hr by agarose gel electrophoresis | Escherichia coli | 1 | ALA4406848 | nucleic acid format | Scientific Literature | |
12. | ALA4409144 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage assessed as linear form at 50 uM irradiated with light and incubated for 1 hr by agarose gel electrophoresis | Escherichia coli | 1 | ALA4406848 | nucleic acid format | Scientific Literature | |
13. | ALA4409145 | Binding | Induction of Escherichia coli plasmid pBR322 DNA cleavage assessed as increase in nicked circular DNA in presence of light irradiation and incubated for 1 hr by agarose gel electrophoresis | Escherichia coli | 1 | ALA4406848 | nucleic acid format | Scientific Literature | |
14. | ALA4409147 | Binding | Inhibition of recombinant human topoisomerase 1 assessed as linear DNA at 50 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 1 | ALA4406848 | single protein format | Scientific Literature | |
15. | ALA4409148 | Binding | Inhibition of recombinant human topoisomerase 1 at 12.50 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | single protein format | Scientific Literature | |
16. | ALA4409149 | Binding | Inhibition of recombinant human topoisomerase 1 at 25 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | single protein format | Scientific Literature | |
17. | ALA4409150 | Binding | Inhibition of recombinant human topoisomerase 1 at 50 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | single protein format | Scientific Literature | |
18. | ALA4409153 | Binding | Inhibition of recombinant human topoisomerase 2 assessed as supercoiled DNA at 50 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | protein format | Scientific Literature | |
19. | ALA4409154 | Binding | Inhibition of recombinant human topoisomerase 2 at 12.5 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | protein format | Scientific Literature | |
20. | ALA4409155 | Binding | Inhibition of recombinant human topoisomerase 2 at 25 uM incubated for 1 hr by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 2 | ALA4406848 | protein format | Scientific Literature |